Kohda Naohisa, Iijima Masahiro, Kawaguchi Kyotaro, Toshima Hirokazu, Muguruma Takeshi, Endo Kazuhiko, Mizoguchi Itaru
Division of Orthodontics and Dentofacial Orthopedics, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Eur J Oral Sci. 2015 Jun;123(3):202-7. doi: 10.1111/eos.12187. Epub 2015 Apr 22.
We investigated the enamel demineralization-prevention ability and shear bond strength (SBS) properties of 4-methacryloxyethyl trimellitic anhydride/methyl methacrylate-tri-n-butyl borane (4-META/MMA-TBB)-based resin containing various amounts (0-50%) of bioactive glass (BG). Disk-shaped specimens were immersed in distilled water and ions released were analysed by inductively coupled plasma atomic-emission spectroscopy. Samples were also immersed in lactic acid solution (pH 4.6) to estimate acid-neutralizing ability. Brackets were bonded to human premolars with BG-containing resins and the bonded teeth were alternately immersed in demineralizing (pH 4.55) and remineralizing (pH 6.8) solutions for 14 d. The enamel hardness was determined by nanoindentation testing at twenty equidistant distances from the external surface. The SBS for each sample was examined. The amounts of ions released [calcium (Ca), sodium (Na), silicon (Si), and boron (B)] and the acid-neutralizing ability increased with increasing BG content. After alternating immersion, the specimens bonded with the BG-containing resin with high BG content were harder than those in the other groups in some locations 1-18.5 μm from the enamel surface. Bioactive glass-containing (10-40%) resin had bond strength equivalent to the control specimen. Thus, the SBS obtained for BG-containing resin (6.5-9.2 MPa) was clinically acceptable, suggesting that this material has the ability to prevent enamel demineralization.
我们研究了含有不同含量（0 - 50%）生物活性玻璃（BG）的4 - 甲基丙烯酰氧乙基偏苯三酸酐/甲基丙烯酸甲酯 - 三正丁基硼烷（4 - META/MMA - TBB）基树脂的防釉质脱矿能力和剪切粘结强度（SBS）特性。将圆盘形试样浸入蒸馏水中，并通过电感耦合等离子体原子发射光谱法分析释放的离子。样品还浸入乳酸溶液（pH 4.6）中以评估其酸中和能力。用含BG的树脂将托槽粘结到人类前磨牙上，然后将粘结的牙齿交替浸入脱矿溶液（pH 4.55）和再矿化溶液（pH 6.8）中14天。通过纳米压痕测试在距外表面二十个等距位置处测定釉质硬度。检查每个样品的SBS。释放的离子量[钙（Ca）、钠（Na）、硅（Si）和硼（B）]以及酸中和能力随BG含量的增加而增加。交替浸泡后，在距釉质表面1 - 18.5μm的某些位置，用高BG含量的含BG树脂粘结的试样比其他组的试样更硬。含生物活性玻璃（10 - 40%）的树脂的粘结强度与对照试样相当。因此，含BG树脂获得的SBS（6.5 - 9.2 MPa）在临床上是可接受的，这表明这种材料具有预防釉质脱矿的能力。
