Kordeluk Sofia, Kraus Mordechai, Leibovitz Eugene
Department of Otorhinolaryngology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel.
Curr Infect Dis Rep. 2015 May;17(5):479. doi: 10.1007/s11908-015-0479-4.
Acute mastoiditis (AM) is a rare but serious complication of otitis media. Recent studies consolidated the role of Streptococcus pyogenes as the second most important etiologic agent of AM and suggested an increased involvement of a relatively new pathogen (Fusobacterium necrophorum). The recently accumulated evidence on AM epidemiology in children is conflicting and not convincing in demonstrating clear trends during the last years. While a significant decrease was recorded in the incidence of pneumococcal invasive disease and complicated AOM following the introduction of the pneumococcal conjugate vaccines, data on the efficacy of these vaccines in the prevention of AM are limited and did not show any remarkable changes in the dynamics of disease caused by Streptococcus pneumoniae. The clinical findings in AM may differ according to the causative pathogen and different patient age subgroups. Together with computerized tomography, magnetic resonance imaging became frequently used, particularly in the diagnosis of AM complications. Simple mastoidectomy remains the most reliable and effective surgical intervention for the treatment of subperiosteal abscesses.
急性乳突炎(AM)是中耳炎一种罕见但严重的并发症。近期研究巩固了化脓性链球菌作为AM第二重要病因的地位,并提示一种相对较新的病原体(坏死梭杆菌)的感染有所增加。最近积累的关于儿童AM流行病学的证据相互矛盾,在证明过去几年的明显趋势方面也缺乏说服力。虽然在引入肺炎球菌结合疫苗后,肺炎球菌侵袭性疾病和复杂性急性中耳炎的发病率显著下降,但这些疫苗在预防AM方面的疗效数据有限,且未显示由肺炎链球菌引起的疾病动态有任何显著变化。AM的临床发现可能因致病病原体和不同的患者年龄亚组而有所不同。与计算机断层扫描一起,磁共振成像也经常被使用,特别是在AM并发症的诊断中。单纯乳突切除术仍然是治疗骨膜下脓肿最可靠、最有效的手术干预方法。