Tamir Sharon Ovnat, Roth Yehudah, Dalal Ilan, Goldfarb Abraham, Marom Tal
Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, Holon, Israel.
Pediatric Allergy/Immunology Unit, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, Holon, Israel.
Clin Vaccine Immunol. 2014 Aug;21(8):1189-91. doi: 10.1128/CVI.00289-14. Epub 2014 Jun 11.
Following the introduction of the 7- and 13-valent pneumococcal conjugate vaccines, we observed an inverse relationship between the increasing rate of immunized children and the proportion of middle ear fluid cultures collected during acute mastoiditis episodes that tested positive for Streptococcus pneumoniae among a subset of children 0 to 6 years old who had initially presented with severe acute otitis media and had bacterial cultures collected during tympanocentesis or from spontaneous otorrhea.
在引入7价和13价肺炎球菌结合疫苗后,我们观察到在最初表现为重度急性中耳炎且在鼓膜穿刺或自流式耳漏时进行了细菌培养的0至6岁儿童亚组中,免疫接种儿童的增加率与急性乳突炎发作期间采集的中耳积液培养物中肺炎链球菌检测呈阳性的比例之间存在反比关系。