Poulsen E
Ministry of Health, Soeborg, Denmark.
Biomed Environ Sci. 1989 Mar;2(1):30-5.
The influence of toxicology on legislation is quite clear in countries where chemicals are regulated by the authorities. There is normally a toxicological evaluation--in addition to other considerations--behind sales and use permissions and the levels that are accepted in food, air, water, etc. How does legislation affect toxicology? If there is no legislation, then clinical and forensic toxicology will be the most used toxicological disciplines (accidents and other cases of poisoning). The more sophisticated and restrictive the legislation becomes, the more toxicology is used not only to permit the use of chemicals but also to ban them. In addition, legislation for the protection of experimental animals has a profound influence in toxicology and accelerates the use of in vitro and other alternative methods. This paper discusses whether countries in the "developed" world are overdoing it, thereby maybe hampering the essential use of chemicals in the developing countries.
在由当局对化学品进行监管的国家，毒理学对立法的影响十分明显。除其他因素外，在销售和使用许可以及食品、空气、水等中可接受的含量背后，通常都有一个毒理学评估。立法如何影响毒理学呢？如果没有立法，那么临床毒理学和法医毒理学将成为最常用的毒理学学科（事故及其他中毒案例）。立法变得越复杂、越严格，毒理学就不仅被用于允许化学品的使用，还被用于禁止化学品的使用。此外，保护实验动物的立法对毒理学有深远影响，并加速了体外及其他替代方法的使用。本文探讨了“发达”世界的国家是否做得过头了，从而可能阻碍发展中国家对化学品的必要使用。
