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姿势性心动过速综合征患者常出现颞下颌关节紊乱疼痛,且明显影响生活质量。

Painful temporomandibular disorders are common in patients with postural orthostatic tachycardia syndrome and impact significantly upon quality of life.

出版信息

J Oral Facial Pain Headache. 2015 Spring;29(2):152-7. doi: 10.11607/ofph.1396.

DOI:10.11607/ofph.1396
PMID:25905533
Abstract

AIMS

To explore the point prevalence of painful temporomandibular disorders (TMD) in a well-characterized clinical cohort of postural orthostatic tachycardia syndrome (PoTS) sufferers and to understand the functional and physiologic impact of this comorbidity on the patient.

METHODS

Patients with PoTS were retrospectively recruited from a previous study conducted in a UK hospital setting. Data had previously been collected on several parameters, including sociodemographic, physiologic, and functional. The participants were mailed a highly sensitive (99%) and specific (97%) self-report screening instrument for painful TMD. Simple descriptive statistics with Fisher Exact and Kruskal-Wallis tests were used to examine the data and draw inferences from it.

RESULTS

A total of 36 individuals responded (69% response rate). Just under half (47%) of the sample screened positive for painful TMD. There was no significant difference between the screening result for TMD or previously reported headaches or joint pain (P < .05). Chronic fatigue syndrome (CFS) was diagnosed by the Fukuda Criteria in 44% of the total sample and in 56% of those with painful TMD. There were no significant differences in physiologic parameters in CFS and TMD. TMD caused a significant decrease in quality of life as measured by the Patient-Reported Outcomes Measurement Information System, Health Assessment Questionnaire (P < .05).

CONCLUSION

TMD are common in patients with PoTS. They have a significant, additional impact on patients' quality of life and should therefore be screened for at an early stage in PoTS.

摘要

目的

在一组特征明确的体位性心动过速综合征(PoTS)患者中,探索疼痛性颞下颌关节紊乱(TMD)的时点患病率,并了解这种合并症对患者的功能和生理影响。

方法

从英国医院进行的先前研究中回顾性招募 PoTS 患者。先前已收集了包括社会人口统计学、生理学和功能等多个参数的数据。研究人员向患者邮寄了一种高度敏感(99%)和特异性(97%)的疼痛性 TMD 自我报告筛查工具。使用Fisher 精确检验和 Kruskal-Wallis 检验进行简单描述性统计,以检查数据并从中得出推论。

结果

共有 36 人(69%的回应率)做出回应。样本中接近一半(47%)的人对 TMD 筛查呈阳性。TMD 的筛查结果与先前报告的头痛或关节痛之间没有显著差异(P<0.05)。在总样本中,44%的人符合福冈标准被诊断为慢性疲劳综合征(CFS),而在有疼痛 TMD 的人中,这一比例为 56%。CFS 和 TMD 患者的生理参数无显著差异。TMD 导致患者的生活质量显著下降,这一点在患者报告的结果测量信息系统和健康评估问卷中得到了体现(P<0.05)。

结论

TMD 在 PoTS 患者中很常见。它们对患者的生活质量有显著的额外影响,因此应在 PoTS 的早期阶段对其进行筛查。

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