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采用气相色谱-离子阱/质谱法测定欧洲市场上用于治疗下尿路症状的草药产品及食品中的植物甾醇。

Determination by GC-IT/MS of phytosterols in herbal medicinal products for the treatment of lower urinary tract symptoms and food products marketed in Europe.

作者信息

Müller Christoph, Bracher Franz

机构信息

Department für Pharmazie, Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität, München, Germany.

出版信息

Planta Med. 2015 May;81(7):613-20. doi: 10.1055/s-0035-1545906. Epub 2015 Apr 23.

DOI:10.1055/s-0035-1545906
PMID:25905593
Abstract

A method for the determination of phytosterols in herbal medicinal products for the treatment of lower urinary tract symptoms and food products is described here. Using a convenient sample preparation protocol and sensitive gas chromatography ion trap mass spectrometry analysis, ten different sterols, among them five Δ(7)-phytosterols as typical constituents of pumpkin seed preparations, could be identified and quantified. This protocol was applied to the analysis of 31 marketed products, from which seven were raw materials.

摘要

本文描述了一种用于测定治疗下尿路症状的草药产品和食品中植物甾醇的方法。采用简便的样品制备方案和灵敏的气相色谱离子阱质谱分析法,可鉴定和定量十种不同的甾醇,其中五种Δ(7)-植物甾醇是南瓜籽制剂的典型成分。该方案应用于31种市售产品的分析,其中七种为原材料。

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