Waldron Mary, Doran Kelly A, Bucholz Kathleen K, Duncan Alexis E, Lynskey Michael T, Madden Pamela A F, Sartor Carolyn E, Heath Andrew C
Department of Counseling and Educational Psychology, School of Education, Bloomington, Indiana University, Indiana; Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Department of Counseling and Educational Psychology, School of Education, Bloomington, Indiana University, Indiana.
J Adolesc Health. 2015 May;56(5):550-6. doi: 10.1016/j.jadohealth.2015.01.011.
We examined timing of first voluntary sexual intercourse as a joint function of parental separation during childhood and parental history of alcoholism.
Data were drawn from a birth cohort of female like-sex twins (n = 569 African ancestry [AA]; n = 3,415 European or other ancestry [EA]). Cox proportional hazards regression was conducted predicting age at first sex from dummy variables coding for parental separation and parental alcoholism. Propensity score analysis was also employed to compare intact and separated families, stratified by predicted probability of separation.
Earlier sex was reported by EA twins from separated and alcoholic families, compared to EA twins from intact nonalcoholic families, with effects most pronounced through the age of 14 years. Among AA twins, effects of parental separation and parental alcoholism were largely nonsignificant. Results of propensity score analyses confirmed unique risks from parental separation in EA families, where consistent effects of parental separation were observed across predicted probability of separation. For AA families, there was poor matching on risk factors presumed to predate separation, which limited interpretability of survival-analytic findings.
In European American families, parental separation during childhood is an important predictor of early-onset sex, beyond parental alcoholism and other correlated risk factors. To characterize risk for African Americans associated with parental separation, additional research is needed where matching on confounders can be achieved.
我们研究了首次自愿性交的时间,将其作为童年时期父母离异和父母酗酒史的联合函数。
数据来自一个女性同性双胞胎出生队列(n = 569 非洲裔 [AA];n = 3415 欧洲或其他裔 [EA])。进行了Cox比例风险回归,根据父母离异和父母酗酒的虚拟变量预测首次性行为的年龄。还采用倾向得分分析来比较完整家庭和离异家庭,并按预测的离异概率进行分层。
与来自完整非酗酒家庭的EA双胞胎相比,来自离异和酗酒家庭的EA双胞胎报告的首次性行为时间更早,这种影响在14岁之前最为明显。在AA双胞胎中,父母离异和父母酗酒的影响大多不显著。倾向得分分析结果证实了EA家庭中父母离异带来的独特风险,在不同预测离异概率的情况下,均观察到了父母离异的一致影响。对于AA家庭,在假定早于离异的风险因素上匹配不佳,这限制了生存分析结果的可解释性。
在欧美家庭中,童年时期父母离异是早发性性行为的重要预测因素,超越了父母酗酒和其他相关风险因素。为了描述非裔美国人与父母离异相关的风险,需要进行更多能够实现混杂因素匹配的研究。