医院环境中家畜相关耐甲氧西林金黄色葡萄球菌的影响。
Impact of livestock-associated MRSA in a hospital setting.
作者信息
van de Sande-Bruinsma Nienke, Leverstein van Hall Maurine A, Janssen Maria, Nagtzaam Nynke, Leenders Sander, de Greeff Sabine C, Schneeberger Peter M
机构信息
Center for Infectious Disease Control, Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Center for Infectious Disease Control, Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands ; Department of Medical Microbiology and Infection Control, Bronovo Hospital, The Hague, The Netherlands.
出版信息
Antimicrob Resist Infect Control. 2015 Apr 17;4:11. doi: 10.1186/s13756-015-0053-8. eCollection 2015.
OBJECTIVES
The Netherlands is known for a stringent search and destroy policy to prevent spread of MRSA. In the hospital setting, livestock-associated MRSA (LA-MRSA) is frequently found in patients coming from the high density farming area in the south of the Netherlands. The aim of the study was to determine the contribution of LA-MRSA in the epidemiology of MRSA in cases found following the Dutch search and destroy policy.
PATIENTS AND METHODS
From two hospitals serving a population of 550,000 persons all data on MRSA cultures and subsequent control measures from 2008 and 2009 were retrospectively collected and analyzed.
RESULTS
A total of 3856 potential index patients were screened for MRSA, 373 (9.7%) were found to be positive, 292 ( 78%) LA-MRSA and 81 (22%) non-LA-MRSA respectively. No secondary cases were found among contact research in persons exposed to LA-MRSA (0/416), whereas similar contact research for non-LA-MRSA resulted in 83 (2.5%) secondary cases. LA-MRSA were rarely found to cause infections.
CONCLUSIONS
LA-MRSA is more prevalent than non-LA-MRSA in Dutch Hospitals in the South of the Netherlands. However, retrospectively studied cases show that the transmission rate for LA-MRSA was much lower than for non-LA-MRSA. This suggest that infection control practices for LA-MRSA may possibly be less stringent than for non-LA-MRSA.
目的
荷兰以严格的筛查和清除政策来预防耐甲氧西林金黄色葡萄球菌（MRSA）传播而闻名。在医院环境中，与牲畜相关的MRSA（LA-MRSA）在来自荷兰南部高密度养殖区的患者中经常被发现。本研究的目的是确定在荷兰筛查和清除政策下发现的病例中，LA-MRSA在MRSA流行病学中的作用。
患者与方法
从两家服务于55万人口的医院回顾性收集并分析了2008年和2009年所有关于MRSA培养及后续控制措施的数据。
结果
共筛查了3856名潜在的索引患者的MRSA，其中373人（9.7%）被发现呈阳性，分别为292人（78%）LA-MRSA和81人（22%）非LA-MRSA。在接触LA-MRSA的人群的接触调查中未发现二代病例（0/416），而对非LA-MRSA进行类似的接触调查则导致83例（2.5%）二代病例。LA-MRSA很少被发现会引起感染。
结论
在荷兰南部的医院中，LA-MRSA比非LA-MRSA更普遍。然而，回顾性研究的病例显示，LA-MRSA的传播率远低于非LA-MRSA。这表明针对LA-MRSA的感染控制措施可能比对非LA-MRSA的措施宽松。
Zotero 插件