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感染性休克:重症监护病房出院后医院死亡的主要原因。

Septic shock: a major cause of hospital death after intensive care unit discharge.

作者信息

Giacomini Matheus Gomes, Lopes Márcia Valéria Caldeira Angelucci, Gandolfi Joelma Villafanha, Lobo Suzana Margareth Ajeje

机构信息

Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil.

Serviço de Terapia Intensiva, Hospital de Base de São José do Rio Preto, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil.

出版信息

Rev Bras Ter Intensiva. 2015 Jan-Mar;27(1):51-6. doi: 10.5935/0103-507X.20150009. Epub 2015 Mar 1.

Abstract

OBJECTIVE

To assess the causes and factors associated with the death of patients between intensive care unit discharge and hospital discharge.

METHODS

The present is a pilot, retrospective, observational cohort study. The records of all patients admitted to two units of a public/private university hospital from February 1, 2013 to April 30, 2013 were assessed. Demographic and clinical data, risk scores and outcomes were obtained from the Epimed monitoring system and confirmed in the electronic record system of the hospital. The relative risk and respective confidence intervals were calculated.

RESULTS

A total of 581 patients were evaluated. The mortality rate in the intensive care unit was 20.8% and in the hospital was 24.9%. Septic shock was the cause of death in 58.3% of patients who died after being discharged from the intensive care unit. Of the patients from the public health system, 73 (77.6%) died in the intensive care unit and 21 (22.4%) died in the hospital after being discharged from the unit. Of the patients from the Supplementary Health System, 48 (94.1%) died in the intensive care unit and 3 (5.9%) died in the hospital after being discharged from the unit (relative risk, 3.87%; 95% confidence interval, 1.21 - 12.36; p < 0.05). The post-discharge mortality rate was significantly higher in patients with intensive care unit hospitalization time longer than 6 days.

CONCLUSION

The main cause of death of patients who were discharged from the intensive care unit and died in the ward before hospital discharge was septic shock. Coverage by the public healthcare system and longer hospitalization time in the intensive care unit were factors associated with death after discharge from the intensive care unit.

摘要

目的

评估重症监护病房出院至医院出院期间患者死亡的原因及相关因素。

方法

本研究为一项前瞻性、回顾性、观察性队列研究。对2013年2月1日至2013年4月30日期间入住一所公立/私立大学医院两个科室的所有患者的记录进行评估。从Epimed监测系统获取人口统计学和临床数据、风险评分及结局,并在医院电子记录系统中进行确认。计算相对风险及各自的置信区间。

结果

共评估了581例患者。重症监护病房的死亡率为20.8%,医院的死亡率为24.9%。脓毒性休克是重症监护病房出院后死亡患者中58.3%的死亡原因。在公共卫生系统的患者中,73例(77.6%)在重症监护病房死亡,21例(22.4%)在从该科室出院后在医院死亡。在补充卫生系统的患者中,48例(94.1%)在重症监护病房死亡,3例(5.9%)在从该科室出院后在医院死亡(相对风险,3.87%;95%置信区间,1.21 - 12.36;p < 0.05)。重症监护病房住院时间超过6天的患者出院后死亡率显著更高。

结论

重症监护病房出院且在医院出院前在病房死亡的患者的主要死亡原因是脓毒性休克。公共医疗系统覆盖范围以及在重症监护病房较长的住院时间是与重症监护病房出院后死亡相关的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f825/4396897/9c9566da89d2/rbti-27-01-0051-g01.jpg

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