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[应用钌(RU 106 Rh 106)治疗100例脉络膜和睫状体黑色素瘤的评估]

[Evaluation of 100 melanomas of the choroid and ciliary body treated by application of ruthenium (RU 106 Rh 106)].

作者信息

Grange J D, Gerard J P, Ragab M, Quintero P, Delaroche G, Jean-Louis B, Sentenac I, Fontaniere B, Bievelez B

出版信息

Bull Soc Ophtalmol Fr. 1989 May;89(5):679-82.

PMID:2590984
Abstract

100 cases of uveal melanomas, were treated with 106 RU 106 RH beta-brachytherapy, between June 1983 and September 1987. 82 eyes having a follow-up superior or equal to 6 months, were analysed. 13 of these 82 eyes have been enucleated. 2 patients, have died, 2 have at this time, hepatic dissemination. The first 43 patients were analysed at the 18th month after irradiation. The majority of tumors with initial thickness inferior to 5 mm had a regression superior to 50%, at the 18th month. The majority of tumors with initial thickness superior to 5 mm, had a regression inferior to 50%, at the same time. Functional results have also been noticed in this series of 43 eyes, and were satisfactory.

摘要

1983年6月至1987年9月期间,100例葡萄膜黑色素瘤患者接受了106Ru和106Rhβ近距离放射治疗。对82只随访时间不少于6个月的眼睛进行了分析。这82只眼中有13只已被摘除眼球。2例患者死亡,2例目前有肝转移。对前43例患者在放疗后第18个月进行了分析。大多数初始厚度小于5mm的肿瘤在第18个月时缩小超过50%。大多数初始厚度大于5mm的肿瘤在同一时间缩小不到50%。在这43只眼中还观察到了功能结果,且结果令人满意。

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