Zimmerman Kurt, Yoder Bradley K
Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Cell. 2015 Apr 23;161(3):692-692.e1. doi: 10.1016/j.cell.2015.04.015.
Primary cilia are cellular appendages that coordinate diverse sensory and signaling activities. They are important for proper mammalian development, adult tissue homeostasis, and vision and odorant detection, and their dysfunction contributes to disease pathology and developmental defects.
初级纤毛是协调多种感觉和信号活动的细胞附属物。它们对于哺乳动物的正常发育、成体组织稳态、视觉和嗅觉检测至关重要,其功能障碍会导致疾病病理和发育缺陷。