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中血管血管炎所致肾梗死

Renal infarction caused by medium vessel vasculitis.

作者信息

Kavarthapol Jayaraman Vinothkumar, Chakera Aron

机构信息

Department of Nephrology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.

出版信息

BMJ Case Rep. 2015 Apr 24;2015:bcr2014208942. doi: 10.1136/bcr-2014-208942.

Abstract

A 44-year-old Italian man presented to the emergency department on three occasions over 4 days with severe left flank pain. Initial investigations including a renal tract ultrasound were normal and he was discharged with analgaesia. On his third presentation, a CT angiogram was performed due to persisting pain, which demonstrated infarction of his left kidney as well as thickening of the anterior branch of left renal artery and complete occlusion with focal intimal dissection of the coeliac artery. His antineutrophil cytoplasmic antibody was negative. A medium vessel vasculitis was suspected and confirmed on positron emission tomography-CT, which revealed increased metabolic activity involving the right internal mammary artery and coeliac artery. Treatment with pulse methylprednisolone was started followed by a tapering prednisolone regimen, with a rapid reduction in his inflammatory indices. Twenty-four months later his renal function remains normal off all immunosuppression.

摘要

一名44岁的意大利男子在4天内三次前往急诊科,主诉左侧腰部剧痛。包括肾脏超声在内的初步检查均正常,他接受镇痛治疗后出院。第三次就诊时,由于疼痛持续,进行了CT血管造影,结果显示左肾梗死,左肾动脉前支增厚,腹腔干动脉完全闭塞并伴有局灶性内膜剥离。他的抗中性粒细胞胞浆抗体呈阴性。怀疑为中血管血管炎,正电子发射断层扫描-CT证实了这一诊断,该检查显示右乳内动脉和腹腔干动脉代谢活性增加。开始使用甲泼尼龙冲击治疗,随后采用逐渐减量的泼尼松龙方案,炎症指标迅速下降。24个月后,在停用所有免疫抑制剂的情况下,他的肾功能仍保持正常。

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本文引用的文献

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Diagnosis and evaluation of vasculitis.血管炎的诊断与评估
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The pathology of vasculitis involving the kidney.累及肾脏的血管炎病理学
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