轻柔采血和试管缓冲可减少气动管道系统对乳酸脱氢酶检测的干扰。
Gentle blood aspiration and tube cushioning reduce pneumatic tube system interference in lactate dehydrogenase assays.
作者信息
Strubi-Vuillaume Isabelle, Carlier Valentine, Obeuf Catherine, Vasseur Francis, Maury J-Claude, Maboudou Patrice, Mangalaboyi Jacques, Durocher Alain, Launay David, Noel Christian, Brousseau Thierry
机构信息
UF 8832 - Biochimie Automatisée, Pôle de Biologie Pathologie Génétique, CHRU de Lille, Lille, France
UF 8832 - Biochimie Automatisée, Pôle de Biologie Pathologie Génétique, CHRU de Lille, Lille, France.
出版信息
Ann Clin Biochem. 2016 Mar;53(Pt 2):295-7. doi: 10.1177/0004563215586600. Epub 2015 Apr 24.
BACKGROUND
Use of a hospital pneumatic tube system may be associated with measurement errors.
METHODS
A venous blood sample was collected from 79 patients into a pair of lithium heparin tubes; one tube was sent to the laboratory by porter and the other was sent via the pneumatic tube system. Plasma lactate dehydrogenase concentrations were then assayed.
RESULTS
Lactate dehydrogenase concentrations were overestimated (median bias: 18.8%) when evacuated vacuum lithium heparin tubes were sent by pneumatic tube system. This bias was reduced by bubble-wrapping the standard lithium heparin tube or using Monovette lithium heparin tubes in aspiration mode (median bias: +8.7% and -0.3%, respectively).
CONCLUSIONS
Cushioning and aspiration-mode sampling may limit pneumatic tube system-associated overestimation of lactate dehydrogenase concentrations.
背景
使用医院气动管道系统可能会导致测量误差。
方法
从79名患者中采集静脉血样本，放入一对含锂肝素的试管中；一个试管由搬运工送到实验室，另一个通过气动管道系统送去。然后测定血浆乳酸脱氢酶浓度。
结果
当使用真空含锂肝素试管通过气动管道系统传送时，乳酸脱氢酶浓度被高估（中位数偏差：18.8%）。通过对标准含锂肝素试管进行气泡包装或使用抽吸模式的莫诺韦特含锂肝素试管，这种偏差有所减小（中位数偏差分别为+8.7%和-0.3%）。
结论
缓冲和抽吸模式采样可能会限制气动管道系统相关的乳酸脱氢酶浓度高估。
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