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马凡综合征、遗传性主动脉病变与运动:正确答案是什么?

Marfan syndrome, inherited aortopathies and exercise: what is the right answer?

作者信息

Cheng Andrew, Owens David

机构信息

Department of Cardiology, VA Puget Sound, Seattle, Washington, USA Department of Cardiology, University of Washington, Seattle, Washington, USA.

Department of Cardiology, University of Washington, Seattle, Washington, USA.

出版信息

Heart. 2015 May 15;101(10):752-7. doi: 10.1136/heartjnl-2014-306440.

DOI:10.1136/heartjnl-2014-306440
PMID:25911666
Abstract

Exercise recommendations for those who have Marfan syndrome or other genetic predisposition for thoracic aortic disease remain controversial and at times ambiguous. There are no outcomes studies to help guide recommendations. In this review, we examine the guidelines regarding exercise and inherited aortic conditions, the theoretical reasoning and circumstantial evidence that support the guidelines, as well as the knowledge gaps that continue to exist.

摘要

对于患有马凡综合征或其他有胸主动脉疾病遗传易感性的人,运动建议仍然存在争议,有时还含糊不清。目前尚无结果研究来帮助指导相关建议。在本综述中,我们审视了有关运动和遗传性主动脉疾病的指南、支持这些指南的理论依据和间接证据,以及仍然存在的知识空白。

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