Heffner Jaimee L, McClure Jennifer B, Mull Kristin E, Anthenelli Robert M, Bricker Jonathan B
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Group Health Research Institute, Seattle, WA, USA.
Bipolar Disord. 2015 Aug;17(5):560-6. doi: 10.1111/bdi.12300. Epub 2015 Apr 25.
People with bipolar disorder are two to three times more likely to smoke and 50% less likely to quit than the general population. New treatments are needed to improve smoking cessation outcomes in this group. The study aim was to develop and pilot test a novel cessation intervention for smokers with bipolar disorder using Acceptance and Commitment Therapy (ACT) combined with nicotine patches.
The ten-session ACT intervention was initially evaluated as in-person, individual counseling (n = 10), then as telephone-delivered counseling (n = 6). Participants were adult smokers with no more than mild current symptoms of bipolar disorder.
For the in-person protocol, end-of-treatment outcomes were: 80% retention, 40% of participants with carbon monoxide (CO)-verified seven-day point prevalence abstinence (PPA), 90% satisfied with treatment, 8.3 of ten sessions attended, and 54% increase in acceptance of cravings to smoke (i.e., ACT's theory-based change process) from baseline. The seven-day PPA at one-month follow-up was 30%. For the telephone protocol, end-of-treatment outcomes were: 67% retention, 33% reporting seven-day PPA, 100% satisfied with treatment, 6.7 of ten treatment calls completed, and 55% increase in acceptance from baseline. At one-month follow-up, seven-day PPA was 17%. The proportion of treatment completers who used at least 80% of the nicotine patches was 62.5% for the in-person protocol and 0% for the telephone protocol.
Both in-person and telephone-delivered ACT were feasible. Despite low adherence to nicotine patches, the intervention showed preliminary evidence of facilitating quitting and impacting ACT's change mechanism. A randomized, controlled trial of this targeted ACT intervention is now needed.
双相情感障碍患者吸烟的可能性是普通人群的两到三倍,且戒烟的可能性比普通人群低50%。需要新的治疗方法来改善该群体的戒烟效果。本研究的目的是开发并试点测试一种针对双相情感障碍吸烟者的新型戒烟干预措施,该措施采用接纳与承诺疗法(ACT)并结合尼古丁贴片。
最初对为期十节的ACT干预措施进行评估时采用面对面的个体咨询(n = 10),之后采用电话咨询(n = 6)。参与者为成年吸烟者,目前双相情感障碍症状不超过轻度。
对于面对面干预方案,治疗结束时的结果为:保留率80%,40%的参与者经一氧化碳(CO)验证实现了七天点患病率戒烟(PPA),90%的人对治疗满意,参加了十节课程中的8.3节,对吸烟渴望的接纳度较基线提高了54%(即ACT基于理论的改变过程)。在一个月的随访中,七天PPA为30%。对于电话干预方案,治疗结束时的结果为:保留率67%,33%的人报告实现了七天PPA,100%的人对治疗满意,完成了十次治疗电话中的6.7次,接纳度较基线提高了55%。在一个月的随访中,七天PPA为17%。对于面对面干预方案,至少使用了80%尼古丁贴片的治疗完成者比例为62.5%,而电话干预方案为0%。
面对面和电话形式的ACT干预都是可行的。尽管对尼古丁贴片的依从性较低,但该干预措施显示出有助于戒烟并影响ACT改变机制的初步证据。现在需要对这种有针对性的ACT干预进行随机对照试验。