Bricker Jonathan B, Bush Terry, Zbikowski Susan M, Mercer Laina D, Heffner Jaimee L
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Psychology, University of Washington, Seattle, WA;
Alere Wellbeing, Seattle, WA.
Nicotine Tob Res. 2014 Nov;16(11):1446-54. doi: 10.1093/ntr/ntu102. Epub 2014 Jun 16.
We conducted a pilot randomized trial of telephone-delivered acceptance and commitment therapy (ACT) versus cognitive behavioral therapy (CBT) for smoking cessation.
Participants were 121 uninsured South Carolina State Quitline callers who were adult smokers (at least 10 cigarettes/day) and who wanted to quit within the next 30 days. Participants were randomized to 5 sessions of either ACT or CBT telephone counseling and were offered 2 weeks of nicotine replacement therapy (NRT).
ACT participants completed more calls than CBT participants (M = 3.25 in ACT vs. 2.23 in CBT; p = .001). Regarding satisfaction, 100% of ACT participants reported their treatment was useful for quitting smoking (vs. 87% for CBT; p = .03), and 97% of ACT participants would recommend their treatment to a friend (vs. 83% for CBT; p = .06). On the primary outcome of intent-to-treat 30-day point prevalence abstinence at 6 months postrandomization, the quit rates were 31% in ACT versus 22% in CBT (odds ratio [OR] = 1.5, 95% confidence interval [CI] = 0.7-3.4). Among participants depressed at baseline (n = 47), the quit rates were 33% in ACT versus 13% in CBT (OR = 1.2, 95% CI = 1.0-1.6). Consistent with ACT's theory, among participants scoring low on acceptance of cravings at baseline (n = 57), the quit rates were 37% in ACT versus 10% in CBT (OR = 5.3, 95% CI = 1.3-22.0).
ACT is feasible to deliver by phone, is highly acceptable to quitline callers, and shows highly promising quit rates compared with standard CBT quitline counseling. As results were limited by the pilot design (e.g., small sample), a full-scale efficacy trial is now needed.
我们开展了一项初步随机试验,比较通过电话提供的接受与承诺疗法(ACT)和认知行为疗法(CBT)在戒烟方面的效果。
参与者为121名南卡罗来纳州未参保的戒烟热线来电者,均为成年吸烟者(每天至少吸10支烟),且希望在未来30天内戒烟。参与者被随机分配接受5次ACT或CBT电话咨询,并提供2周的尼古丁替代疗法(NRT)。
ACT组参与者完成的电话咨询次数多于CBT组(ACT组平均为3.25次,CBT组为2.23次;p = 0.001)。在满意度方面,100%的ACT组参与者表示他们的治疗对戒烟有用(CBT组为87%;p = 0.03),97%的ACT组参与者会向朋友推荐他们接受的治疗(CBT组为83%;p = 0.06)。在随机分组后6个月的意向性治疗30天点患病率戒烟这一主要结局指标上,ACT组的戒烟率为31%,CBT组为22%(优势比[OR] = 1.5,95%置信区间[CI] = 0.7 - 3.4)。在基线时抑郁的参与者(n = 47)中,ACT组的戒烟率为33%,CBT组为13%(OR = 1.2,95%CI = 1.0 - 1.6)。与ACT理论一致,在基线时对渴望接受程度得分较低的参与者(n = 57)中,ACT组的戒烟率为37%,CBT组为10%(OR = 5.3,95%CI = 1.3 - 22.0)。
通过电话提供ACT是可行的,戒烟热线来电者对其接受度很高,与标准的CBT戒烟热线咨询相比,显示出非常有前景的戒烟率。由于结果受初步设计(如样本量小)限制,现在需要进行全面的疗效试验。