State Key Laboratory of Plant Genomics and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology (IGDB), Chinese Academy of Sciences (CAS), Beijing, China.
CAS Key Laboratory for Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences (CAS), Shanghai, China.
J Pineal Res. 2015 Aug;59(1):91-101. doi: 10.1111/jpi.12243. Epub 2015 May 19.
Melatonin, an antioxidant in both animals and plants, has been reported to have beneficial effects on the aging process. It was also suggested to play a role in extending longevity and enhancing abiotic stress resistance in plant. In this study, we demonstrate that melatonin acts as a potent agent to delay leaf senescence and cell death in rice. Treatments with melatonin significantly reduced chlorophyll degradation, suppressed the transcripts of senescence-associated genes, delayed the leaf senescence, and enhanced salt stress tolerance. Genome-wide expression profiling by RNA sequencing reveals that melatonin is a potent free radical scavenger, and its exogenous application results in enhanced antioxidant protection. Leaf cell death in noe1, a mutant with over-produced H2O2, can be relieved by exogenous application of melatonin. These data demonstrate that melatonin delays the leaf senescence and cell death and also enhances abiotic stress tolerance via directly or indirectly counteracting the cellular accumulation of H2O2.
褪黑素是动植物体内的一种抗氧化剂，据报道对衰老过程有有益的影响。它还被认为在延长植物寿命和增强非生物胁迫抗性方面发挥作用。在这项研究中，我们证明褪黑素可作为一种有效物质来延缓水稻叶片衰老和细胞死亡。褪黑素处理显著降低了叶绿素降解，抑制了衰老相关基因的转录，延缓了叶片衰老，并增强了耐盐胁迫能力。通过 RNA 测序的全基因组表达谱分析表明，褪黑素是一种有效的自由基清除剂，其外源应用可增强抗氧化保护。过量产生 H2O2 的 noe1 突变体的叶片细胞死亡可以通过外源褪黑素处理得到缓解。这些数据表明，褪黑素通过直接或间接抵消 H2O2 的细胞积累来延缓叶片衰老和细胞死亡，并增强非生物胁迫耐受性。
