Suryadevara Manika, Domachowske Joseph B
a Department of Pediatrics; SUNY Upstate Medical University ; Syracuse , NY , USA.
Hum Vaccin Immunother. 2015;11(7):1744-7. doi: 10.1080/21645515.2015.1038442.
Pertussis is a vaccine preventable respiratory infection. Young infants are at high risk of developing severe complications from infection. Despite high rates of pediatric vaccine uptake, there continues to be increases in pertussis cases, likely due to waning immunity from childhood vaccine and increased transmission through adults. Currently, pertussis booster vaccine (Tdap) is recommended for unimmunized adults and for women in the third trimester of each pregnancy; yet adult Tdap coverage remains low. Administering Tdap vaccine at non-traditional vaccination clinics and at sites where adults are accessing care for their children are effective in improving adult Tdap uptake. While most are willing to receive vaccine when recommended by their provider, lack of provider recommendation is a major obstacle to immunization. Future studies to understand barriers to provider vaccine recommendations need to be undertaken to develop interventions to improve adult Tdap vaccine uptake and reduce pertussis infection in the susceptible population.
百日咳是一种可通过疫苗预防的呼吸道感染。小婴儿感染后发生严重并发症的风险很高。尽管儿童疫苗接种率很高,但百日咳病例仍在增加,这可能是由于儿童疫苗免疫力下降以及通过成人传播增加所致。目前,建议未接种疫苗的成年人以及每次怀孕第三个月的妇女接种百日咳加强疫苗(Tdap);然而,成人Tdap疫苗接种率仍然很低。在非传统疫苗接种诊所和成人带孩子就医的场所接种Tdap疫苗,可有效提高成人Tdap疫苗接种率。虽然大多数人愿意在医生建议下接种疫苗,但缺乏医生的建议是免疫接种的主要障碍。需要开展未来研究,以了解医生疫苗建议的障碍,从而制定干预措施,提高成人Tdap疫苗接种率,并减少易感人群中的百日咳感染。