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造血干细胞移植后出现的一种罕见并发症:韦尼克脑病。

A Rare Complication Developing After Hematopoietic Stem Cell Transplantation: Wernicke's Encephalopathy.

作者信息

Solmaz Soner, Gereklioğlu Çiğdem, Tan Meliha, Demir Şenay, Yeral Mahmut, Korur Aslı, Boğa Can, Özdoğu Hakan

机构信息

Adana Hospital of Başkent University, Department of Hematology, Adana, Turkey Phone: +90 322 327 27 27 E-mail:

出版信息

Turk J Haematol. 2015 Dec;32(4):367-70. doi: 10.4274/tjh.2014.0412. Epub 2015 Apr 27.

Abstract

Thiamine is a water-soluble vitamin. Thiamine deficiency can present as a central nervous system disorder known as Wernicke's encephalopathy, which classically manifests as confusion, ataxia, and ophthalmoplegia. Wernicke's encephalopathy has rarely been reported following hematopoietic stem cell transplantation. Herein, we report Wernicke's encephalopathy in a patient with acute myeloid leukemia who had been receiving prolonged total parenteral nutrition after haploidentical allogeneic hematopoietic stem cell transplantation. To the best of our knowledge, this is the first case reported from Turkey in the literature.

摘要

硫胺素是一种水溶性维生素。硫胺素缺乏可表现为一种称为韦尼克脑病的中枢神经系统疾病,其典型表现为意识模糊、共济失调和眼肌麻痹。造血干细胞移植后很少有韦尼克脑病的报道。在此,我们报告一例急性髓系白血病患者在单倍体异基因造血干细胞移植后接受长期全胃肠外营养后发生韦尼克脑病。据我们所知,这是土耳其文献中报道的首例病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bcf/4805320/914a8de815c9/TJH-32-367-g1.jpg

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