Enck P, Kuhlbusch R, Lübke H, Frieling T, Erckenbrecht J F
University Hospital, Department of Internal Medicine, Düsseldorf, Federal Republic of Germany.
Dis Colon Rectum. 1989 Dec;32(12):1026-30. doi: 10.1007/BF02553874.
Although the prevalence of fecal incontinence is greater in women compared with men and in elderly subjects compared with younger subjects, data regarding the influence of age and sex on anorectal performance in continent and incontinent patients are conflicting. The authors, therefore, investigated age- and gender-related changes in anal resting and squeeze pressure as well as in sphincter relaxation after rectal balloon distention in 75 patients with fecal incontinence of different pathogenesis and in 99 continent patients by multichannel anorectal manometry. As a group, incontinent patients usually exhibit lower pressure profiles than do continent patients regardless of age and gender; however, both the resting pressure of the internal anal sphincter and the voluntary contractile pressure of the external anal sphincter are decreased with age, and both are lowered in women compared with men. Sphincter relaxation and perception of gastrointestinal events are not altered in incontinent patients, and they are not different between men and women or between elderly and younger patients.
尽管女性大便失禁的患病率高于男性，老年受试者高于年轻受试者，但关于年龄和性别对大便能自控和大便失禁患者肛门直肠功能影响的数据存在矛盾。因此，作者通过多通道肛门直肠测压法，对75例不同发病机制的大便失禁患者和99例大便能自控患者，研究了年龄和性别相关的肛门静息压、收缩压以及直肠球囊扩张后括约肌松弛情况的变化。总体而言，无论年龄和性别，大便失禁患者的压力曲线通常低于大便能自控患者；然而，随着年龄增长，肛门内括约肌的静息压和肛门外括约肌的自主收缩压均降低，且女性低于男性。大便失禁患者的括约肌松弛和对胃肠道事件的感知未改变，男女之间以及老年和年轻患者之间也无差异。
