Hathorn M K
Department of Physiology, London Hospital Medical College.
Early Hum Dev. 1989 Nov;20(2):81-99. doi: 10.1016/0378-3782(89)90050-9.
Spectral analysis was performed on ventilation and instantaneous heart rate data recorded in 15 term infants during quiet sleep in the first week after delivery, and in 11 of these infants during active sleep. There was a close relation between the main peaks of the ventilation spectra and the corresponding histograms of the reciprocals of Ttot. The spectra for instantaneous heart rate showed power at the rate of breathing (HF) and also at lower frequencies, 0.04-0.2 Hz (LF). During quiet sleep, the relative magnitudes of the HF and LF peaks for heart rate were found to depend on the respiratory rate and the variability of Ttot. During active sleep, most of the power in the heart rate spectrum was concentrated in the LF region. Weighted coherences between ventilation and heart rate were higher during quiet than active sleep, both in the HF and LF spectra. LF power was higher during active than quiet sleep in both ventilation and heart rate. The results suggest that the pattern of breathing has a marked effect on the shape of the heart rate spectrum. In most infants, however, there is no fixed phase relationship between oscillations in ventilation and heart rate, at high or low frequencies. These oscillations are affected by sleep state and hence, by implication, by central nervous system rhythm generators.
对15名足月儿出生后第一周安静睡眠期间以及其中11名婴儿活跃睡眠期间记录的通气和瞬时心率数据进行了频谱分析。通气频谱的主峰与Ttot倒数的相应直方图之间存在密切关系。瞬时心率频谱在呼吸频率（HF）以及较低频率0.04 - 0.2Hz（LF）处显示出功率。在安静睡眠期间，发现心率的HF和LF峰的相对大小取决于呼吸频率和Ttot的变异性。在活跃睡眠期间，心率频谱中的大部分功率集中在LF区域。在HF和LF频谱中，安静睡眠期间通气与心率之间的加权相干性高于活跃睡眠期间。在通气和心率方面，活跃睡眠期间的LF功率均高于安静睡眠期间。结果表明呼吸模式对心率频谱的形状有显著影响。然而，在大多数婴儿中，通气和心率的振荡在高频或低频时不存在固定的相位关系。这些振荡受睡眠状态影响，因此，含蓄地说，受中枢神经系统节律发生器影响。
