Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997 (Russia) http://yampolsky.ibch.ru.
Pirogov Russian National Research Medical University, Ostrovitianov 1, Moscow 117997 (Russia).
Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7065-7. doi: 10.1002/anie.201501668. Epub 2015 Apr 27.
A novel luciferin from a bioluminescent Siberian earthworm Fridericia heliota was recently described. In this study, the Fridericia oxyluciferin was isolated and its structure elucidated. The results provide insight into a novel bioluminescence mechanism in nature. Oxidative decarboxylation of a lysine fragment of the luciferin supplies energy for light generation, while a fluorescent CompX moiety remains intact and serves as the light emitter.
最近描述了一种来自发光的西伯利亚蚯蚓 Fridericia heliota 的新型荧光素。在这项研究中，分离出了 Fridericia 氧化荧光素，并阐明了其结构。研究结果为自然界中的一种新的生物发光机制提供了深入了解。荧光素赖氨酸片段的氧化脱羧为发光提供能量，而完整的荧光 CompX 部分作为发光体。
