Cozzolino Immacolata, Zeppa Pio, Zabatta Assunta, Merolla Francesco, Vetrani Antonio, Sadile Francesco
Cytopathology Service, Department of Public Health, Azienda Ospedaliera Universitaria "Federico II", 80131, Napoli, Italy.
Department of Medicine and Surgery, University of Salerno, Baronissi, Italy.
Diagn Cytopathol. 2015 Sep;43(9):734-8. doi: 10.1002/dc.23286. Epub 2015 Apr 25.
We report seven cases of chondroblastoma (CB) of bone, diagnosed by Fine-Needle Aspiration Cytology (FNAC), and confirmed by histomorphological examination. The concurrence of some cytomorphologic findings - mononucleated cells, multinucleated cells, and intercellular chondroid substance - unequivocally suggested the cytological diagnosis of CB. We also reviewed the literature on this topic in order to discuss morphological criteria and the importance of needle size. The differential diagnosis between CB, Giant Cell Tumor of Bone, and Eosinophilic Granuloma is further discussed.
我们报告了7例经细针穿刺细胞学检查（FNAC）诊断并经组织形态学检查确诊的骨软骨母细胞瘤（CB）。一些细胞形态学表现——单核细胞、多核细胞和细胞间软骨样物质同时出现——明确提示了CB的细胞学诊断。我们还回顾了关于该主题的文献，以讨论形态学标准和针大小的重要性。进一步讨论了CB、骨巨细胞瘤和嗜酸性肉芽肿之间的鉴别诊断。
