食管胃交界部癌的治疗：一场未解决的争论。
Treatment of esophagogastric junction carcinoma: an unsolved debate.
作者信息
Orditura Michele, Galizia Gennaro, Lieto Eva, De Vita Ferdinando, Ciardiello Fortunato
机构信息
Michele Orditura, Ferdinando De Vita, Fortunato Ciardiello, Division of Medical Oncology, Department of Internal and Experimental Medicine "F. Magrassi", School of Medicine, Second University of Naples, 80131 Naples, Italy.
出版信息
World J Gastroenterol. 2015 Apr 21;21(15):4427-31. doi: 10.3748/wjg.v21.i15.4427.
The incidence of esophagogastric junction adenocarcinoma (AEG) is increasing worldwide. Barrett's esophagus (BE) associated with dysplasia is the main risk factor for the development of cancer. Currently, screening programs to individuate and eradicate BE represent the best way to reduce AEG cancer. Several endoscopic approaches are here discussed. Surgical strategies for different types of AEG cancer are now fairly standardized, and multidisciplinary strategies using chemotherapy or chemoradiotherapy may improve the outcome of these patients. Here we briefly discuss the keypoints, main topics, and critical issues, according to accumulating evidence and taking into account our own experience.
食管胃交界腺癌（AEG）的发病率在全球范围内呈上升趋势。与发育异常相关的巴雷特食管（BE）是癌症发生的主要危险因素。目前，识别和消除BE的筛查计划是降低AEG癌症的最佳方法。本文讨论了几种内镜治疗方法。不同类型AEG癌症的手术策略现已相当标准化，使用化疗或放化疗的多学科策略可能会改善这些患者的治疗效果。在此，我们根据积累的证据并结合我们自己的经验，简要讨论要点、主要话题和关键问题。
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