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本文引用的文献

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Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration: Two-Year Results.雷珠单抗和贝伐单抗治疗新生血管性年龄相关性黄斑变性:两年结果。
Ophthalmology. 2020 Apr;127(4S):S135-S145. doi: 10.1016/j.ophtha.2020.01.029.
2
Topical bevacizumab for neovascular glaucoma: a pilot study.局部应用贝伐单抗治疗新生血管性青光眼:一项初步研究。
Pharmacology. 2014;93(3-4):108-12. doi: 10.1159/000358600. Epub 2014 Feb 20.
3
High-dose topical bevacizumab for corneal neovascularization.高剂量局部贝伐单抗治疗角膜新生血管。
Pharmacology. 2013;92(5-6):310-4. doi: 10.1159/000356407. Epub 2013 Dec 4.
4
Pharmacokinetics of bevacizumab after topical and intravitreal administration in human eyes.贝伐单抗经眼部局部和玻璃体内给药后的药代动力学。
Graefes Arch Clin Exp Ophthalmol. 2014 Feb;252(2):331-7. doi: 10.1007/s00417-013-2495-0. Epub 2013 Oct 31.
5
Intracameral bevacizumab as an adjunct to trabeculectomy: a 1-year prospective, randomised study.眼内注射贝伐单抗作为小梁切除术的辅助治疗:一项为期 1 年的前瞻性随机研究。
Br J Ophthalmol. 2014 Jan;98(1):73-8. doi: 10.1136/bjophthalmol-2013-303966. Epub 2013 Oct 24.
6
Age-related macular degeneration.年龄相关性黄斑变性。
Lancet. 2012 May 5;379(9827):1728-38. doi: 10.1016/S0140-6736(12)60282-7.
7
Corneal penetration of topical and subconjunctival bevacizumab.贝伐单抗滴眼和球结膜下给药的角膜穿透性。
Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8718-23. doi: 10.1167/iovs.11-7871.
8
Ranibizumab and bevacizumab for neovascular age-related macular degeneration.雷珠单抗和贝伐单抗治疗新生血管性年龄相关性黄斑变性。
N Engl J Med. 2011 May 19;364(20):1897-908. doi: 10.1056/NEJMoa1102673. Epub 2011 Apr 28.
9
Pharmacotherapy for neovascular age-related macular degeneration: an analysis of the 100% 2008 medicare fee-for-service part B claims file.抗新生血管治疗年龄相关性黄斑变性的药物治疗:对 2008 年 100%的医疗保险服务费用 B 部分索赔文件的分析。
Am J Ophthalmol. 2011 May;151(5):887-895.e1. doi: 10.1016/j.ajo.2010.11.017. Epub 2011 Feb 18.
10
Corneal Melt While Using Topical Bevacizumab Eye Drops.使用局部贝伐单抗滴眼液时出现角膜溶解。
Ophthalmic Surg Lasers Imaging. 2010 Mar 9:1-3. doi: 10.3928/15428877-20100215-07.

贝伐单抗在难治性青光眼治疗中的临床应用。

Clinical use of Bevacizumab in treating refractory glaucoma.

作者信息

Popescu V, Pricopie S, Totir M, Iancu R, Yasyn S, Alexandrescu C

机构信息

Anatomy Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Department of Clinical Ophthalmology, University Emergency Hospital Bucharest, Romania.

出版信息

J Med Life. 2015 Jan-Mar;8(1):8-12.

PMID:25914729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4397528/
Abstract

UNLABELLED

Bevacizumab is a recombinant humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF). Though other VEGF inhibitors are being approved for the treatment of ophthalmological conditions, bevacizumab found its way into ophthalmology and clinical practice all around the world. The objective of this review is to present the ophthalmic dosage and administration pathways of bevacizumab in treating refractory glaucoma patients.

ABBREVIATIONS

VEGF = vascular endothelial growth factor, FDA = Food and Drug Administration, AMD = age-related macular degeneration.

摘要

未标注

贝伐单抗是一种针对血管内皮生长因子(VEGF)的重组人源化单克隆抗体。尽管其他VEGF抑制剂正在被批准用于治疗眼科疾病,但贝伐单抗已进入全球眼科和临床实践。本综述的目的是介绍贝伐单抗在治疗难治性青光眼患者中的眼科剂量和给药途径。

缩写

VEGF = 血管内皮生长因子,FDA = 食品药品监督管理局,AMD = 年龄相关性黄斑变性