Dekio S, Nagashima T, Watanabe Y, Jidoi J
Department of Dermatology, Shimane Medical University, Izumo, Japan.
Dermatologica. 1989;179(3):118-22. doi: 10.1159/000248336.
S-carboxymethylated (SCM) fibrous proteins from the scalp hair of a patient with hypotrichosis with keratosis pilaris (HTKP) and from that of a normal individual were analyzed using two-dimensional electrophoresis. One SCM fibrous protein component was different electrophoretically in the HTKP patient. It is suggested that the brittleness of the HTKP hair might result from this alteration of the fibrous protein composition of the hair.
使用二维电泳分析了一名患有毛发角化病伴少毛症（HTKP）患者和一名正常个体头皮毛发中的S-羧甲基化（SCM）纤维蛋白。在HTKP患者中，一种SCM纤维蛋白成分在电泳上有所不同。提示HTKP毛发的脆性可能是由毛发纤维蛋白组成的这种改变所致。
