Dharmaratne Ranjith W
, 35, Sri Thapodarama Road, Hanthana, Kandy, 20000, Sri Lanka,
Environ Health Prev Med. 2015 Jul;20(4):237-42. doi: 10.1007/s12199-015-0464-4. Epub 2015 Apr 28.
A significant number of people in the North Central Province of Sri Lanka suffer from chronic kidney diseases (CKD), and the author revisits existing literature related to CKD to find its causative factor. There is a direct connection between high fluoride levels in drinking water and kidney disease, and there are unhealthy levels of fluoride in the groundwater in Sri Lanka's CKD-affected areas. Based on the following observations, the author believes with confidence that excess fluoride in drinking water and in the locally grown food in the affected areas are the culprits of CKD in Sri Lanka. Fluoride excretion rate is considerably lower in children than adults, leading to renal damage of children living in areas with high fluoride. Adults who had renal damage due to fluoride in childhood are vulnerable to CKD with continued consumption of water from the same source. Patients with chronic renal insufficiency are at an increased risk of chronic fluoride toxicity. High content of fluoride in groundwater paves the way to excess fluoride in local food crops, consequently adding more fluoride to the systems of the consumers. People who work outdoors for prolonged periods consume excess water and tea, and are subjected to additional doses of fluoride in their system. In the mid-1980s, the increase in water table levels of the affected areas due to new irrigation projects paved the way to adding more fluorides to their system through drinking water and locally grown foods.
斯里兰卡中北部省份有相当数量的人患有慢性肾病(CKD),作者重新审视了与CKD相关的现有文献以找出其致病因素。饮用水中高氟含量与肾脏疾病之间存在直接联系,并且在斯里兰卡受CKD影响地区的地下水中氟含量处于不健康水平。基于以下观察结果,作者坚信受影响地区饮用水和当地种植食物中的过量氟是斯里兰卡CKD的罪魁祸首。儿童的氟排泄率明显低于成年人,这会导致生活在高氟地区的儿童肾脏受损。童年时期因氟而肾脏受损的成年人,若继续饮用同一水源的水,则易患CKD。慢性肾功能不全患者慢性氟中毒的风险增加。地下水中的高氟含量导致当地粮食作物中氟过量,从而使消费者体内摄入更多氟。长时间在户外工作的人饮用过量的水和茶,体内会摄入额外剂量的氟。在20世纪80年代中期,新的灌溉项目导致受影响地区地下水位上升,通过饮用水和当地种植的食物使人们体内摄入更多氟。