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胸壁骨合成术后钛植入物失败

Titanium Implant Failure After Chest Wall Osteosynthesis.

作者信息

Berthet Jean-Philippe, Gomez Caro Abel, Solovei Laurence, Gilbert Matthieu, Bommart Sébastien, Gaudard Philippe, Canaud Ludovic, Alric Pierre, Marty-Ané Charles-Henri

机构信息

Thoracic Surgery Department, University Hospital Arnaud de Villeneuve, Montpellier, France; U1046, INSERM, Montpellier University, Montpellier, France.

General Thoracic Surgery Department, Hospital Clinic, University of Barcelona, Barcelona, Spain.

出版信息

Ann Thorac Surg. 2015 Jun;99(6):1945-52. doi: 10.1016/j.athoracsur.2015.02.040. Epub 2015 Apr 24.

Abstract

BACKGROUND

Our objective was to assess potential contributing factors to implant failure (displacement or rupture) after titanium chest wall osteosynthesis.

METHODS

We retrospectively reviewed the clinical data and preoperative and postoperative computed tomographic scans of patients undergoing chest wall osteosynthesis with titanium implants: the Stratos or the Matrix Fixation System in two European departments of thoracic surgery. The indications for titanium chest wall osteosynthesis, the type and number of implants, the topography of the reconstruction, surgical site infection, and role of associated flap and mesh were assessed.

RESULTS

Between January 2009 and January 2013, 54 patients underwent osteosynthesis after surgical correction of chest wall deformities (n = 25, 46.2%) or to bridge the defect after tumor removal (n = 29, 53.7%). The topography of osteosynthesis was anterior (n = 20), lateral (n = 3), or posterior (n = 1), an average of 1.9 ± 0.9 implants (range, 1 to 5 implants) being used. A combined mesh restored continuity of the chest wall in 15 patients, and muscle flap coverage was performed in 20. The mean follow-up time was 20.2 ± 8.4 months (range, 3 to 48 months). Among these 54 patients, 24 (44%) experienced an implant failure. Seven (29%) were symptomatic. Broken (n = 20, 83.3%) or displaced (n = 4, 16.7%) implants were removed with or without replacement. In patients with broken or displaced implants, the mean duration without implant failure was 6.6 ± 3.1 months (range, 1 to 12 months). There was a significant relationship between the anterior topography of osteosynthesis and implant failure (p = 0.02).

CONCLUSIONS

Long-term follow-up after chest wall osteosynthesis using titanium implants is required, especially in anteriorly placed implants. The high rate of implant failure at 1 year advocates for early removal whenever possible and suggests the need for improvements in design.

摘要

背景

我们的目的是评估钛合金胸壁骨固定术后植入物失败(移位或破裂)的潜在影响因素。

方法

我们回顾性分析了两个欧洲胸外科科室中接受胸壁钛合金植入物骨固定术患者的临床资料以及术前和术后的计算机断层扫描结果,这些植入物为Stratos或Matrix固定系统。评估了钛合金胸壁骨固定术的适应证、植入物的类型和数量、重建部位、手术部位感染以及相关皮瓣和补片的作用。

结果

2009年1月至2013年1月期间,54例患者在胸壁畸形手术矫正后(n = 25,46.2%)或肿瘤切除后填补缺损时(n = 29,53.7%)接受了骨固定术。骨固定部位为前部(n = 20)、外侧(n = 3)或后部(n = 1),平均使用1.9±0.9枚植入物(范围为1至5枚植入物)。15例患者使用补片联合修复胸壁连续性,20例患者进行了肌皮瓣覆盖。平均随访时间为20.2±8.4个月(范围为3至48个月)。在这54例患者中,24例(44%)出现植入物失败。7例(29%)有症状。取出了破裂(n = 20,83.3%)或移位(n = 4,16.7%)的植入物,部分进行了更换。在植入物破裂或移位的患者中,无植入物失败的平均持续时间为6.6±3.1个月(范围为1至12个月)。骨固定部位在前部与植入物失败之间存在显著相关性(p = 0.02)。

结论

使用钛合金植入物进行胸壁骨固定术后需要长期随访,尤其是在前部植入的情况下。1年时较高的植入物失败率主张尽可能早期取出,并提示需要改进设计。

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