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自发性气胸的流行病学:与性别相关的差异。

Epidemiology of spontaneous pneumothorax: gender-related differences.

机构信息

Service de Chirurgie Thoracique, Hôpitaux Universitaires Paris Centre, AP-HP, Paris, France.

Centre d'Epidémiologie Clinique, Hôpitaux Universitaires Paris Centre, AP-HP, Paris, France Inserm U1153, Paris, France Université Paris Descartes, PRES Sorbonne Paris Cité, Paris, France.

出版信息

Thorax. 2015 Jul;70(7):653-8. doi: 10.1136/thoraxjnl-2014-206577. Epub 2015 Apr 27.

DOI:10.1136/thoraxjnl-2014-206577
PMID:25918121
Abstract

BACKGROUND

Epidemiology of spontaneous pneumothorax has been scantily studied. We aimed to assess the incidence of spontaneous pneumothorax and describe patients' characteristics with respect to age, sex, seasonal occurrence, primary or secondary character, surgical management and rehospitalisations on a large-scale database.

METHODS

Data from all patients aged ≥14 years and hospitalised with a diagnosis of non-traumatic pneumothorax in France from 2008 to 2011 were retrieved from the National Hospitalisation Database.

RESULTS

There were 59 637 hospital stays corresponding to 42 595 patients. Twenty-eight per cent of patients were rehospitalised at least once during the 4-year period. Annual rate of pneumothorax could be estimated at 22.7 (95% CI 22.4 to 23.0) cases for 100 000 habitants. The women to men ratio was 1:3.3. Mean age was significantly higher in women than in men (41±19 vs 37±19 years, p<0.0001). No seasonal variation was observed. A surgical procedure was performed in 14 352 hospital stays (24%). In the group of patients aged <30 years, there was no statistical difference between men and women with regard to type of pneumothorax (primary or secondary), type of hospitalisation unit (surgery vs medicine), treatment modality (surgery or not), intensive care unit (ICU) admission and hospital stay duration. Rehospitalisation was more frequent in women than in men (56% vs 52%, p<0.0001). In the 30-49 years age group, surgery and rehospitalisation were more frequent in women than in men (each, p<0.001). In the 50-64 years age group, surgical procedures and rehospitalisations were more frequent in men than in women (p=0.002 and p<0.0001, respectively).

CONCLUSIONS

Sex and age are determinant factors in the course of spontaneous pneumothorax.

摘要

背景

自发性气胸的流行病学研究甚少。我们旨在评估自发性气胸的发病率,并根据年龄、性别、季节发生、原发性或继发性、手术管理和再入院情况,在一个大型数据库中描述患者的特征。

方法

从 2008 年至 2011 年法国国家住院数据库中检索了所有年龄≥14 岁并因非创伤性气胸住院的患者数据。

结果

共有 59637 次住院,涉及 42595 名患者。28%的患者在 4 年内至少再入院一次。气胸的年发生率估计为每 100000 居民 22.7(95%置信区间 22.4 至 23.0)例。女性与男性的比例为 1:3.3。女性的平均年龄明显高于男性(41±19 岁比 37±19 岁,p<0.0001)。未观察到季节性变化。14352 次住院(24%)进行了手术。在年龄<30 岁的患者中,男性和女性气胸类型(原发性或继发性)、住院科室(外科与内科)、治疗方式(手术或非手术)、重症监护病房(ICU)入院和住院时间无统计学差异。女性的再入院率高于男性(56%比 52%,p<0.0001)。在 30-49 岁年龄组中,女性的手术和再入院率高于男性(均为 p<0.001)。在 50-64 岁年龄组中,男性的手术和再入院率高于女性(p=0.002 和 p<0.0001)。

结论

性别和年龄是自发性气胸病程的决定因素。

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