Stanford Cancer Center, Stanford, CA.
J Clin Oncol. 2015 Jun 1;33(16):1855-63. doi: 10.1200/JCO.2014.60.2532. Epub 2015 Apr 27.
We have come a long way in our understanding and treatment of neuroendocrine tumors since the term "karzinoide" was coined in 1907. Neuroendocrine tumors are a group of biologically and clinically heterogeneous neoplasms that most commonly originate in the lungs, GI tract, and pancreas. The selection of initial and subsequent therapies requires careful consideration of both tumor and treatment characteristics. With recent advances, we now have more tools for the diagnosis and treatment of our patients. This comprehensive review article summarizes recent advances in the field of neuroendocrine tumors and places them into context for best management practices.
自 1907 年提出“类癌”一词以来，我们对神经内分泌肿瘤的理解和治疗已经取得了很大的进展。神经内分泌肿瘤是一组生物学和临床特征均具有异质性的肿瘤，最常见的起源于肺、胃肠道和胰腺。初始和后续治疗的选择需要仔细考虑肿瘤和治疗的特点。随着最近的进展，我们现在有更多的工具来诊断和治疗我们的患者。本文综述了神经内分泌肿瘤领域的最新进展，并结合最佳管理实践进行了讨论。
