Guzel Ali Irfan, Erkılınc Selcuk, Ozer Irfan, Tokmak Aytekin, Kurt Sahin Ayse, Ugur Mustafa
Division of Infertility and Gynecological Endocrinology, Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey.
Int J Fertil Steril. 2015 Apr-Jun;9(1):41-6. doi: 10.22074/ijfs.2015.4207. Epub 2015 Apr 21.
We conducted this prospective study to evaluate the prognostic significance of uterine and ovarian artery Doppler velocimetry in clomiphene citrate (CC) cycles.
A total of 80 patients with unexplained infertility were given 100 mg/day of CC from day 3 to day 7 of their cycles in this current prospective study. On cycle day 3, before administration of CC, each patient underwent Doppler transvaginal ultrasonography. The Doppler velocimetries of the right and left uterine and ovarian arteries were recorded and analyzed in association with demographic and clinical parameters.
TheThere were 6 out of 80 patients who became pregnant, the overall pregnancy rate in this population was 7.5% for the current study. The cases were divided into two groups according to whether they became pregnant or not. Demographic characteristics showed no statistically significant differences between these groups (p>0.05). However, the duration of infertility did show statistically significant differences between the groups. Doppler velocimetry was not statistically significantly different between the two groups.
Doppler velocimetry of the uterine and ovarian arteries is not a factor in the prognosis for pregnancy in CC cycles.
我们开展这项前瞻性研究以评估枸橼酸氯米芬(CC)周期中子宫和卵巢动脉多普勒测速的预后意义。
在这项当前的前瞻性研究中,共有80例不明原因不孕症患者在其周期的第3天至第7天给予每日100mg的CC。在周期第3天,在给予CC之前,每位患者接受经阴道多普勒超声检查。记录并分析左右子宫和卵巢动脉的多普勒测速,并与人口统计学和临床参数相关联。
80例患者中有6例怀孕,本研究中该人群的总体妊娠率为7.5%。根据是否怀孕将病例分为两组。这些组之间的人口统计学特征无统计学显著差异(p>0.05)。然而,不孕持续时间在两组之间确实显示出统计学显著差异。两组之间的多普勒测速无统计学显著差异。
子宫和卵巢动脉的多普勒测速不是CC周期中妊娠预后的一个因素。