Zhao Y F, Yang J J, Yang Z H, Hou C L, Deng K H, Zhang X H
Hua Xi Yi Ke Da Xue Xue Bao. 1989 Jun;20(2):211-3.
Primary pulmonary cryptococcal granuloma is not common in Sichuan. The diagnosis of this disease is difficult to make because the patient has no characteristic symptoms and the chest X-ray findings of the mass are not easily differentiated from carcinoma of the lung. The incidence of this disease is apparently increasing. Pulmonary cryptococcosis may be disseminated hematogenously to the meninges and cryptococcal meningitis is very difficult to treat. If the pulmonary lesion is localized, the patient's general condition is good with no evidence of systemic lupus erythematosis, diabetes, leukemia or lymphoma, partial resection of the lung is indicated. But, if the patient has a history of recent cryptococcal meningitis, surgery must be deferred. Four cases of primary pulmonary cryptococcal granuloma have been treated surgically supplemented with medical therapy in the First Affiliated Hospital from 1986 to 1987. Follow-up of more than one year showed good results in each case.
原发性肺隐球菌肉芽肿在四川并不常见。该病的诊断较为困难,因为患者没有特征性症状,且肺部肿块的胸部X线表现不易与肺癌相鉴别。该病的发病率明显呈上升趋势。肺隐球菌病可能通过血行播散至脑膜,而隐球菌性脑膜炎很难治疗。如果肺部病变局限,患者一般状况良好,且无系统性红斑狼疮、糖尿病、白血病或淋巴瘤的证据,则适合行肺部分切除术。但是,如果患者近期有隐球菌性脑膜炎病史,则必须推迟手术。1986年至1987年,第一附属医院对4例原发性肺隐球菌肉芽肿患者进行了手术治疗,并辅以药物治疗。随访一年以上,每例患者效果良好。