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并发中枢神经系统和支气管内结核,酷似转移性肺癌。

Concurrent central nervous system and endobronchial tuberculosis mimicking a metastatic lung cancer.

作者信息

Ciftci Fatma, Shimbori Naoto, Karnak Demet

机构信息

Department of Chest Disease, Ankara University School of Medicine, Ankara, Turkey.

Department of Internal Medicine, Ankara University School of Medicine, Ankara, Turkey.

出版信息

Clin Respir J. 2017 Jan;11(1):98-102. doi: 10.1111/crj.12311. Epub 2015 May 22.

Abstract

BACKGROUND AND AIMS

Early diagnosis and treatment of central nervous system tuberculosis are important because of high mortality and morbidity. Airways must be carefully evaluated in differential diagnosis.

METHODS

We present a rare case of intracranial-endobronchial tuberculosis mimicking lung cancer with brain metastasis.

RESULTS

A vegetative mass lesion, confirmed as necrotic granulomatous inflammation, originating from the entrance of the right upper lobe entry, was coagulated and extracted by argon plasma coagulation and cryotherapy to prevent permanent upper lobe atelectasis. Mycobacterium tuberculosis complex was detected in bronchoscopic material. A four-drug initial anti-tuberculous treatment regimen was given in 2 months. The upper lobe atelectasis was resolved at the fourth month of therapy despite upper lobar bronchus patency. The patient was doing well and completed the two-drug maintenance therapy of 7 months with complete resolution.

CONCLUSION

In such cases, tissue diagnosis should be achieved as early as possible and anti-tuberculous treatment was commenced along with advanced interventional techniques.

摘要

背景与目的

由于中枢神经系统结核病的高死亡率和高发病率,其早期诊断和治疗至关重要。在鉴别诊断时必须仔细评估气道情况。

方法

我们报告一例罕见的颅内-支气管内结核病例,该病例酷似伴有脑转移的肺癌。

结果

一个源于右上叶入口处的赘生物样肿块病变,经证实为坏死性肉芽肿性炎症,通过氩等离子体凝固术和冷冻疗法进行凝固和切除,以防止上叶永久性肺不张。在支气管镜检查材料中检测到结核分枝杆菌复合群。最初给予为期2个月的四联抗结核治疗方案。尽管上叶支气管通畅,但在治疗的第四个月上叶肺不张得到缓解。患者情况良好,完成了为期7个月的二联维持治疗,完全康复。

结论

在这类病例中,应尽早进行组织诊断,并结合先进的介入技术开始抗结核治疗。

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