Hong Sung-Won, Linton John A, Shim Jae-Yong, Kang Hee-Taik
Health Promotion Center, Chung-Ang University Medical Center, Seoul, Republic of Korea; Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea.
International Health Care Center, Severance Hospital, College of Medicine, Yonsei University, Seoul, Republic of Korea.
Alcohol. 2015 May;49(3):275-81. doi: 10.1016/j.alcohol.2015.02.004. Epub 2015 Mar 12.
We examined the association between alcohol-drinking pattern and diabetes mellitus (DM) in Korean adults. This cross-sectional study included 12,486 participants (5551 men and 6935 women) who participated in the 2010-2012 Korean National Health and Nutrition Examination Survey. We categorized alcohol-drinking pattern into three groups based on the alcohol-use disorders identification test (AUDIT): low-risk (score: 0-7), intermediate-risk (score: 8-14), and high-risk (score: ≥15). DM was defined as having fasting plasma glucose ≥126 mg/dL or taking glucose-lowering medication, including insulin therapy. In the study population, 25.2% of men and 4.7% of women were high-risk drinkers. DM prevalence was 9.2% in men and 5.4% in women. DM prevalence was 9.0% and 5.7% in the low-risk drinking group, 7.6% and 4.1% in the intermediate-risk drinking group, and 11.2% and 3.5% in the high-risk drinking group in men and women, respectively. Compared to the low-risk drinking group, odds ratios (95% confidence intervals) of men and women in the intermediate-risk drinking group for DM were 1.043 (0.779-1.396) and 1.139 (0.712-1.824), respectively, and 1.480 (1.133-1.933) and 0.827 (0.296-2.311) in the high-risk drinking group, after adjusting for age and other confounding factors. In conclusion, high-risk drinking appears to be associated with a higher risk of DM in men, but not in women.
我们研究了韩国成年人饮酒模式与糖尿病（DM）之间的关联。这项横断面研究纳入了12486名参与者（5551名男性和6935名女性），他们参加了2010 - 2012年韩国国家健康与营养检查调查。我们根据酒精使用障碍识别测试（AUDIT）将饮酒模式分为三组：低风险（得分：0 - 7）、中度风险（得分：8 - 14）和高风险（得分：≥15）。糖尿病被定义为空腹血糖≥126mg/dL或正在服用降糖药物，包括胰岛素治疗。在研究人群中，25.2%的男性和4.7%的女性为高风险饮酒者。男性糖尿病患病率为9.2%，女性为5.4%。男性和女性低风险饮酒组的糖尿病患病率分别为9.0%和5.7%，中度风险饮酒组分别为7.6%和4.1%，高风险饮酒组分别为11.2%和3.5%。在调整年龄和其他混杂因素后，与低风险饮酒组相比，中度风险饮酒组男性和女性患糖尿病的优势比（95%置信区间）分别为1.043（0.779 - 1.396）和1.139（0.712 - 1.824），高风险饮酒组分别为1.480（1.133 - 1.933）和0.827（0.296 - 2.311）。总之，高风险饮酒似乎与男性患糖尿病的较高风险相关，但与女性无关。
