Narula Kanika, Pandey Aarti, Gayali Saurabh, Chakraborty Niranjan, Chakraborty Subhra
National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India.
National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India.
J Proteomics. 2015 Sep 8;127(Pt A):34-43. doi: 10.1016/j.jprot.2015.04.020. Epub 2015 Apr 25.
In the post-genomic era, proteomics is acknowledged as the next frontier for biological research. Although India has a long and distinguished tradition in protein research, the initiation of proteomics studies was a new horizon. Protein research witnessed enormous progress in protein separation, high-resolution refinements, biochemical identification of the proteins, protein-protein interaction, and structure-function analysis. Plant proteomics research, in India, began its journey on investigation of the proteome profiling, complexity analysis, protein trafficking, and biochemical modeling. The research article by Bhushan et al. in 2006 marked the birth of the plant proteomics research in India. Since then plant proteomics studies expanded progressively and are now being carried out in various institutions spread across the country. The compilation presented here seeks to trace the history of development in the area during the past decade based on publications till date. In this review, we emphasize on outcomes of the field providing prospects on proteomic pathway analyses. Finally, we discuss the connotation of strategies and the potential that would provide the framework of plant proteome research.
The past decades have seen rapidly growing number of sequenced plant genomes and associated genomic resources. To keep pace with this increasing body of data, India is in the provisional phase of proteomics research to develop a comparative hub for plant proteomes and protein families, but it requires a strong impetus from intellectuals, entrepreneurs, and government agencies. Here, we aim to provide an overview of past, present and future of Indian plant proteomics, which would serve as an evaluation platform for those seeking to incorporate proteomics into their research programs. This article is part of a Special Issue entitled: Proteomics in India.
在后基因组时代，蛋白质组学被公认为是生物学研究的下一个前沿领域。尽管印度在蛋白质研究方面有着悠久而卓越的传统，但蛋白质组学研究的启动却是一个新的领域。蛋白质研究在蛋白质分离、高分辨率改进、蛋白质的生化鉴定、蛋白质 - 蛋白质相互作用以及结构 - 功能分析等方面取得了巨大进展。印度的植物蛋白质组学研究始于对蛋白质组图谱分析、复杂性分析、蛋白质运输和生化建模的研究。布尚等人在2006年发表的研究文章标志着印度植物蛋白质组学研究的诞生。从那时起，植物蛋白质组学研究逐渐扩展，目前正在全国不同机构开展。本文的汇编旨在根据迄今发表的文献追溯该领域在过去十年的发展历程。在这篇综述中，我们强调该领域的研究成果，为蛋白质组学途径分析提供前景。最后，我们讨论策略的内涵以及为植物蛋白质组研究提供框架的潜力。
在过去几十年中，已测序的植物基因组和相关基因组资源数量迅速增加。为了跟上这一不断增长的数据量，印度正处于蛋白质组学研究的初步阶段，旨在建立一个植物蛋白质组和蛋白质家族的比较中心，但这需要知识分子、企业家和政府机构的大力推动。在这里，我们旨在概述印度植物蛋白质组学的过去、现在和未来，这将为那些寻求将蛋白质组学纳入其研究计划的人提供一个评估平台。本文是名为《印度的蛋白质组学》的特刊的一部分。
