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小儿炎症性肠病:具有针对性解决方案的影像学问题

Pediatric inflammatory bowel disease: imaging issues with targeted solutions.

作者信息

Anupindi Sudha A, Podberesky Daniel J, Towbin Alexander J, Courtier Jesse, Gee Michael S, Darge Kassa, Dillman Jonathan R

机构信息

Department of Radiology, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 34th Street and Civic Center Blvd, Philadelphia, PA, 19104, USA,

出版信息

Abdom Imaging. 2015 Jun;40(5):975-92. doi: 10.1007/s00261-015-0423-y.

Abstract

To date, there have been many advances in inflammatory bowel disease (IBD) imaging in every cross-sectional imaging modality, particularly in children. The main emphasis in pediatric IBD imaging is on robust and reproducible measures of small bowel Crohn's disease inflammation, accurate diagnosis of IBD-related complications, and minimizing radiation burden to the patient, as repeat imaging is necessary over the course of their disease. In this article, we discuss the current state-of-the-art imaging techniques, in addition to routine fluoroscopy, including MR and CT enterography and bowel ultrasound. We also present the emerging use of new methods to characterize disease severity and distinguish active inflammation from fibrosis such as diffusion-weighted imaging, bowel elastography, and contrast-enhanced ultrasound. The diagnostic performance of particular examinations, their strengths and weaknesses, and role in IBD management will be discussed. Although these advanced imaging techniques applied to children are similar to those performed in adults, special considerations related to their application in pediatric patients will also be reviewed.

摘要

迄今为止,炎症性肠病(IBD)的各种横断面成像方式都取得了许多进展,尤其是在儿童中。儿科IBD成像的主要重点在于对小肠克罗恩病炎症进行可靠且可重复的测量、准确诊断IBD相关并发症以及将患者的辐射负担降至最低,因为在其病程中需要重复成像。在本文中,除了常规荧光透视检查外,我们还讨论了当前的先进成像技术,包括磁共振和CT小肠造影以及肠道超声。我们还介绍了新方法在表征疾病严重程度以及区分活动性炎症与纤维化方面的新兴应用,如扩散加权成像、肠道弹性成像和超声造影。将讨论特定检查的诊断性能、其优缺点以及在IBD管理中的作用。尽管应用于儿童的这些先进成像技术与应用于成人的技术相似,但也将回顾与它们在儿科患者中的应用相关的特殊注意事项。

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