Trück Johannes, Rampton Charlotte, Kelly Susan Jane, Kelly Dominic
Department of Paediatrics, Paediatric Infectious Diseases and Immunology, University of Oxford, Oxford, UK.
Paediatric Services, Stoke Mandeville Hospital, Aylesbury, UK.
BMJ Case Rep. 2015 Apr 28;2015:bcr2015209484. doi: 10.1136/bcr-2015-209484.
Imported leishmaniasis is rare in non-endemic countries such as the UK. Visceral leishmaniasis (VL) can be life-threatening and its recognition is imperative for successful clinical management. We present a case of VL in an 11-month-old infant several months after returning from a 1-week holiday trip to the South of Spain. The infant suffered from intermittent fever for 5 weeks, and hepatosplenomegaly and pancytopenia, and was successfully treated with a short course of liposomal amphotericin B. This case of VL is to highlight the possibility of transmission of unusual pathogens when travelling to the Mediterranean and therefore the importance of taking a detailed travel history. VL should be considered in the differential diagnosis in returning travellers presenting with prolonged fever, hepatosplenomegaly and/or pancytopenia.
输入性利什曼病在英国等非流行国家较为罕见。内脏利什曼病(VL)可能危及生命,对其进行识别对于成功的临床管理至关重要。我们报告一例11个月大婴儿的VL病例,该婴儿在从西班牙南部为期1周的度假旅行返回几个月后发病。该婴儿间歇性发热5周,伴有肝脾肿大和全血细胞减少,经短期脂质体两性霉素B治疗成功。该VL病例旨在强调前往地中海地区旅行时感染不寻常病原体的可能性,因此详细询问旅行史非常重要。对于出现长期发热、肝脾肿大和/或全血细胞减少的归国旅行者,鉴别诊断时应考虑VL。