Kjær Anne Sofie Høgh Kølbæk, Østergaard Helena Bleken
Infektionsmedicinsk Afdeling Q, Aarhus Universitetshospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N.
Ugeskr Laeger. 2015 Apr 20;177(17).
The symposium IAS Towards an HIV Cure was held in Melbourne, Australia, in July 2014. There are several challenges regarding an HIV cure, among these the reservoir of latently infected CD4+ T cells which are hidden from the immune system. A new promising approach towards an HIV cure is the "shock and kill" strategy. Here, the latently infected cells are shocked to express HIV on the surface, and afterwards the shocked cells can be eradicated by apoptosis or destruction by the immune system. In this paper the most important results from the symposium are presented.
2014年7月，“迈向治愈艾滋病毒”国际艾滋病学会研讨会在澳大利亚墨尔本举行。在实现治愈艾滋病毒方面存在若干挑战，其中包括潜伏感染的CD4+ T细胞库，这些细胞对免疫系统隐藏起来。一种有前景的治愈艾滋病毒的新方法是“激活并清除”策略。在此策略中，潜伏感染的细胞被激活，使其在表面表达艾滋病毒，然后被激活的细胞可通过凋亡或被免疫系统破坏而清除。本文介绍了该研讨会的最重要成果。
