非处方减肥药诱发的荨麻疹性血管炎：一例报告
Urticarial vasculitis induced by OTC diet pills: a case report.
作者信息
Chérrez Ojeda Iván, Loayza Enrique, Greiding Leonardo, Calderón Juan Carlos, Cherrez Annia, Adum Farid
机构信息
School of Medicine, Universidad Espíritu Santo, Guayaquil, Ecuador ; RespiraLab Research Group, Hospital-Clínica Kennedy, Guayaquil, Ecuador.
Centro Dermatológico Loayza, Guayaquil, Ecuador.
出版信息
World Allergy Organ J. 2015 Apr 16;8(1):12. doi: 10.1186/s40413-015-0059-y. eCollection 2015.
BACKGROUND
Urticarial Vasculitis (UV) is in most of the cases idiopathic; however it has been associated with several conditions and drugs. Over the counter (OTC) diet pills are widely available, even on-line, but they are rarely regulated by pharmaceutical control.
CASE PRESENTATION
We present the case of a 35-year-old female patient suffering of pruriginous and painful wheals more than 1 cm in diameter, with a burning sensation. The eruption lasted more than 24 hours and was accompanied by angioedema, headache and myalgia. No remarkable medical history was found, except for previous intake of OTC diet pills. UV diagnosis was confirmed by the skin biopsy of a lesion.
CONCLUSION
OTC diet pills are widely available worldwide, and due to its widespread use, allergologists and dermatologist should be able to recognize symptoms and lesions of cutaneous vasculitis, which may be under reported.
背景
大多数情况下，荨麻疹性血管炎（UV）是特发性的；然而，它与多种病症和药物有关。非处方（OTC）减肥药广泛可得，甚至在网上也能买到，但它们很少受到药品监管。
病例报告
我们报告一例35岁女性患者，其出现直径超过1厘米的瘙痒性疼痛风团，并伴有烧灼感。皮疹持续超过24小时，并伴有血管性水肿、头痛和肌痛。除了之前服用过非处方减肥药外，未发现明显的病史。通过对一处皮损进行皮肤活检确诊为荨麻疹性血管炎。
结论
非处方减肥药在全球广泛可得，由于其广泛使用，过敏症专科医生和皮肤科医生应能够识别可能未得到充分报告的皮肤血管炎症状和皮损。
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