El-Qutob David
University Hospital La Plana, Carretera Vila-Real to Burriana km 0.5, Vila-Real, 12540, Spain.
Ther Adv Vaccines. 2015 Mar;3(2):41-7. doi: 10.1177/2051013614565354.
Ragweeds are flowering plants in the genus Ambrosia in the aster family, Asteraceae. They are distributed in the tropical and subtropical regions of the New World, especially North America. Short ragweed is the most important weed. The ragweed flowering occurs late in the summer and the pollination period extends from the beginning of August to mid-October. Sensitization to ragweed pollen has risen in United States in the past decade and probably worldwide. The major allergenic compound in the pollen has been identified as Amb a 1. Ragweed allergies usually cause allergic rhinitis and asthma. Ragweed allergic patients may show signs of oral allergy syndrome caused by crossreactivity between ragweed allergens and food allergens. In the present article, an update about vaccine development and new knowledge for ragweed allergy is exhaustively revised.
豚草是菊科豚草属的开花植物。它们分布于新大陆的热带和亚热带地区，尤其是北美洲。短叶豚草是最重要的杂草。豚草在夏末开花，授粉期从8月初持续到10月中旬。在过去十年中，美国对豚草花粉的致敏率有所上升，可能在全球范围内也是如此。花粉中的主要致敏化合物已被鉴定为Amb a 1。豚草过敏通常会导致过敏性鼻炎和哮喘。豚草过敏患者可能会出现由豚草过敏原与食物过敏原交叉反应引起的口腔过敏综合征症状。在本文中，对豚草过敏疫苗研发的最新情况和新知识进行了详尽修订。
