Ono Takeshi, Yuki Kenya, Asaoka Ryo, Kouyama Keisuke, Abe Takayuki, Tanabe Sachiko, Fukagawa Kazumi, Uchino Miki, Shimoyama Masaru, Ozawa Yoko, Ozeki Naoki, Shiba Daisuke, Tsubota Kazuo
Department of Ophthalmology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
J Ophthalmol. 2015;2015:497067. doi: 10.1155/2015/497067. Epub 2015 Apr 1.
Purpose. This study examined the association between the severity of visual field defects and the prevalence of motor vehicle collisions (MVCs) in subjects with primary open-angle glaucoma (POAG). Methods. This is a cross-sectional study. Japanese patients who have had driver's licence between 40 and 85 years of age were screened for eligibility. Participants answered a questionnaire about MVCs experienced during the previous 5 years. Subjects with POAG were classified as having mild, moderate, or severe visual field defect. We evaluated associations between the severity of POAG and the prevalence of MVCs by logistic regression models. Results. The prevalence of MVCs was significantly associated with the severity of POAG categorized by worse eye MD (control: 30/187 = 16.0%; mild POAG: 17/92 = 18.5%; moderate POAG: 14/60 = 23.3%; severe POAG: 14/47 = 29.8%; P = 0.025, Cochran-Armitage trend test). Compared to the control group, the adjusted OR for MVC prevalence in subjects with mild, moderate, or severe POAG in the worse eye was 1.07 (95% CI: 0.55 to 2.10), 1.44 (95% CI: 0.68 to 3.08), and 2.28 (95% CI: 1.07 to 4.88). Conclusions. There is a significant association between the severity of glaucoma in the worse eye MD and the prevalence of MVCs.
目的。本研究调查了原发性开角型青光眼（POAG）患者视野缺损的严重程度与机动车碰撞事故（MVC）发生率之间的关联。方法。这是一项横断面研究。对40至85岁持有驾驶执照的日本患者进行资格筛查。参与者回答了一份关于过去5年中经历的MVC的问卷。POAG患者被分类为有轻度、中度或重度视野缺损。我们通过逻辑回归模型评估POAG严重程度与MVC发生率之间的关联。结果。MVC的发生率与根据较差眼平均缺损（MD）分类的POAG严重程度显著相关（对照组：30/187 = 16.0%；轻度POAG：17/92 = 18.5%；中度POAG：14/60 = 23.3%；重度POAG：14/47 = 29.8%；P = 0.025， Cochr an - Armitage趋势检验）。与对照组相比，较差眼中患有轻度、中度或重度POAG的受试者发生MVC的校正比值比分别为1.07（95%可信区间：0.55至2.10）、1.44（95%可信区间：0.68至3.08）和2.28（95%可信区间：1.07至4.88）。结论。较差眼MD中青光眼的严重程度与MVC的发生率之间存在显著关联。
