Szcześniak Dorota, Jawiarczyk-Przybyłowska Aleksandra, Rymaszewska Joanna
Division of Consulting Psychiatry and Neurobiological Research, Department of Psychiatry, Wroclaw Medical University, Poland.
Department of Endocrinology, Diabetology and Isotope Therapy, Wroclaw Medical University, Poland.
Adv Clin Exp Med. 2015 Jan-Feb;24(1):167-72. doi: 10.17219/acem/38156.
Acromegaly is a rare and chronic disease, most often caused by a pituitary adenoma. Excessive secretion of the growth hormone (GH) leads to hepatic secretion of insulin-like growth factor-1 (IGF-1), which in turn causes characteristic changes in the patient's appearance, many skeletal deformities and metabolic disorders. In addition to somatic symptoms, acromegalic patients demonstrate psychosocial and personality deficits, as well as common co-occurrence of mental disorders. There are few studies investigating acromegaly in Poland. In recent years, the concept of quality of life has become fundamental to understanding health problems. Studies dealing with acromegaly likewise tend to include assessments of quality of life of patients suffering from this endocrinopathy.
肢端肥大症是一种罕见的慢性疾病，最常见的病因是垂体腺瘤。生长激素（GH）分泌过多会导致肝脏分泌胰岛素样生长因子-1（IGF-1），进而引起患者外貌的特征性变化、许多骨骼畸形和代谢紊乱。除了躯体症状外，肢端肥大症患者还表现出心理社会和人格缺陷，以及精神障碍的常见共病情况。在波兰，很少有研究调查肢端肥大症。近年来，生活质量的概念已成为理解健康问题的基础。关于肢端肥大症的研究同样倾向于纳入对患有这种内分泌疾病的患者生活质量的评估。
