Gärtner Florian C, Buermann Jens, Skowasch Dirk, Biersack Hans-Jürgen, Essler Markus
Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Bonn.
Klinik und Poliklinik für Allgemein-, Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Bonn.
Dtsch Med Wochenschr. 2015 Apr;140(9):679-83. doi: 10.1055/s-0041-101521. Epub 2015 Apr 29.
The precise staging of lymph-node and distant metastases is pivotal for the choice of surgical procedures and overall therapy planning for patients with lung cancer. FDG-PET/CT plays a central role in the diagnostic algorithm of patients with potentially curable disease. In patients with histologically proven lung cancer, FDG-PET/CT provides a higher diagnostic accuracy in the staging of lymph-node and distant metastases compared to staging with CT alone. Furthermore, as a whole body examination, FDG-PET/CT may replace further additional examinations. Prospective studies have also shown that the number of unnecessary thoracotomies and mediastinoscopies can be reduced by the inclusion of FDG-PET in the preoperative staging.
淋巴结及远处转移的精确分期对于肺癌患者手术方式的选择及整体治疗方案的规划至关重要。氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）在潜在可治愈疾病患者的诊断流程中发挥着核心作用。对于组织学确诊的肺癌患者，与单纯CT分期相比，FDG-PET/CT在淋巴结及远处转移分期方面具有更高的诊断准确性。此外，作为一项全身检查，FDG-PET/CT可能会取代其他额外的检查。前瞻性研究还表明，术前分期纳入FDG-PET可减少不必要的开胸手术和纵隔镜检查的数量。
