Maes Evelyne, Cho William C, Baggerman Geert
Center for Proteomics, University of Antwerp/Flemish Institute for Technological Research (VITO), Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Expert Rev Proteomics. 2015 Jun;12(3):217-9. doi: 10.1586/14789450.2015.1041512. Epub 2015 Apr 30.
Mass spectrometry-based clinical proteomics approaches were introduced into the biomedical field more than two decades ago. Despite recent developments both in the field of mass spectrometry and bioinformatics, the gap between proteomics results and their translation into clinical practice still needs to be closed, as implementation of proteomics results in the clinic appears to be scarce. An extra focus on the importance of the experimental design is therefore of crucial importance.
基于质谱的临床蛋白质组学方法在二十多年前就被引入生物医学领域。尽管近年来质谱领域和生物信息学都有了发展，但蛋白质组学结果与将其转化为临床实践之间的差距仍有待弥合，因为蛋白质组学结果在临床中的应用似乎很少。因此，格外关注实验设计的重要性至关重要。
