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亚太国家儿童特应性皮炎的治疗与疾病经济负担

Treatment of childhood atopic dermatitis and economic burden of illness in Asia Pacific countries.

作者信息

Lee Bee Wah, Detzel Patrick R

出版信息

Ann Nutr Metab. 2015;66 Suppl 1:18-24. doi: 10.1159/000370221. Epub 2015 Apr 24.

Abstract

Atopic dermatitis (AD) is a common chronic inflammatory skin condition in children. In Asia, the prevalence of AD is increasing, which is largely attributed to environmental and socioeconomic factors including family income, parental education, lifestyle and metropolitan living. Current clinical guidelines recommend a stepped approach in the management of eczema in children, with treatment steps tailored to the severity of the eczema. To address the skin barrier dysfunction, skin hydration and the application of emollients is essential. There is evidence supporting the use of bleach baths as an antimicrobial therapy against Staphylococcus aureus. In patients in whom topical treatment fails, wet wrap therapy may be considered as a treatment option before considering systemic therapies. In the second part of this article, the economic burden of AD is addressed. AD not only negatively impacts the child's quality of life but also that of the whole family and is associated with a burden on health-care costs and society. AD in an infant will lead to frequent additional visits to the pediatrician, to additional and partially expensive treatment costs and, in rare cases, to hospitalization. It is thus of utmost importance to define efficient strategies to not only treat AD but also to decrease the risk of developing the disease.

摘要

特应性皮炎(AD)是儿童常见的慢性炎症性皮肤病。在亚洲,AD的患病率正在上升,这在很大程度上归因于环境和社会经济因素,包括家庭收入、父母教育程度、生活方式和大都市生活。当前的临床指南建议对儿童湿疹采用分级治疗方法,治疗步骤根据湿疹的严重程度进行调整。为解决皮肤屏障功能障碍问题,皮肤保湿和使用润肤剂至关重要。有证据支持使用漂白浴作为针对金黄色葡萄球菌的抗菌疗法。对于局部治疗无效的患者,在考虑全身治疗之前,可将湿敷疗法作为一种治疗选择。在本文的第二部分,将探讨AD的经济负担。AD不仅会对儿童的生活质量产生负面影响,还会影响整个家庭的生活质量,并且与医疗保健成本和社会负担相关。婴儿患AD会导致频繁额外就诊于儿科医生,产生额外且部分昂贵的治疗费用,在极少数情况下还会导致住院。因此,确定不仅能治疗AD而且能降低发病风险的有效策略至关重要。

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