Yin Yong-Qin, Pan Jie-Tao, Yu Bang-Wei, Cui Hong-Hua, Yan You-Shao, Chen Yan-Fen
a Department of Traditional Chinese Medicinal Chemistry , Guangdong Pharmaceutical University , Guangzhou 510006 , People's Republic of China.
Nat Prod Res. 2016;30(1):20-4. doi: 10.1080/14786419.2015.1030739. Epub 2015 Apr 30.
Two new compounds of acutacosides 1 and 2, pentasaccharide resin glycosides were isolated from the aerial parts of Argyreia acuta. The core of the two compounds was operculinic acid A, and they were esterfied at the same position, just one substituent group was linked at C-2 of Rha. The absolute configuration of the aglycone in the two compounds was established by Mosher's method, which was (11S)-hydroxyhexadecanoic acid (jalapinolic acid). Their structures were established by a combination of spectroscopic and chemical methods.
从尖锐叶银背藤的地上部分分离出两种新的化合物——刺五加苷1和2，即五糖树脂糖苷。这两种化合物的核心是开螺酸A，它们在相同位置被酯化，只是在鼠李糖的C-2位连接了一个取代基。通过莫舍尔法确定了这两种化合物中苷元的绝对构型，为(11S)-羟基十六烷酸（加拉品醇酸）。它们的结构通过光谱和化学方法相结合得以确定。
