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健康素养与死亡率:一项针对因急性心力衰竭住院患者的队列研究。

Health literacy and mortality: a cohort study of patients hospitalized for acute heart failure.

作者信息

McNaughton Candace D, Cawthon Courtney, Kripalani Sunil, Liu Dandan, Storrow Alan B, Roumie Christianne L

机构信息

Department of Emergency Medicine, Vanderbilt University, Nashville, TN (C.D.M.N., A.B.S.).

Department of Medicine, Vanderbilt University, Nashville, TN (C.C., S.K., C.L.R.).

出版信息

J Am Heart Assoc. 2015 Apr 29;4(5):e001799. doi: 10.1161/JAHA.115.001799.

Abstract

BACKGROUND

More than 30% of patients hospitalized for heart failure are rehospitalized or die within 90 days of discharge. Lower health literacy is associated with mortality among outpatients with chronic heart failure; little is known about this relationship after hospitalization for acute heart failure.

METHODS AND RESULTS

Patients hospitalized for acute heart failure and discharged home between November 2010 and June 2013 were followed through December 31, 2013. Nurses administered the Brief Health Literacy Screen at admission; low health literacy was defined as Brief Health Literacy Screen ≤9. The primary outcome was all-cause mortality. Secondary outcomes were time to first rehospitalization and, separately, time to first emergency department visit within 90 days of discharge. Cox proportional hazards models determined their relationships with health literacy, adjusting for age, gender, race, insurance, education, comorbidity, and hospital length of stay. For the 1379 patients, average age was 63.1 years, 566 (41.0%) were female, and 324 (23.5%) had low health literacy. Median follow-up was 20.7 months (interquartile range 12.8 to 29.6 months), and 403 (29.2%) patients died. Adjusted hazard ratio [aHR] for death among patients with LHL was 1.32 (95%confidence interval [CI] 1.05, 1.66, P=0.02) compared to BHLS>9 [corrected].Within 90 days of discharge, there were 415 (30.1%) rehospitalizations and 201 (14.6%) emergency department visits, with no evident association with health literacy.

CONCLUSIONS

Lower health literacy was associated with increased risk of death after hospitalization for acute heart failure. There was no evident relationship between health literacy and 90-day rehospitalization or emergency department visits.

摘要

背景

因心力衰竭住院的患者中,超过30%在出院后90天内再次住院或死亡。健康素养较低与慢性心力衰竭门诊患者的死亡率相关;而对于急性心力衰竭住院后的这种关系,人们了解甚少。

方法与结果

对2010年11月至2013年6月期间因急性心力衰竭住院并出院回家的患者进行随访,直至2013年12月31日。护士在入院时进行简短健康素养筛查;健康素养低定义为简短健康素养筛查得分≤9分。主要结局是全因死亡率。次要结局分别是首次再住院时间以及出院后90天内首次急诊就诊时间。Cox比例风险模型确定了它们与健康素养的关系,并对年龄、性别、种族、保险、教育程度、合并症和住院时间进行了校正。在1379例患者中,平均年龄为63.1岁,566例(41.0%)为女性,324例(23.5%)健康素养低。中位随访时间为20.7个月(四分位间距12.8至29.6个月),403例(29.2%)患者死亡。与简短健康素养筛查得分>9分[校正后]的患者相比,健康素养低的患者死亡的校正风险比[aHR]为1.32(95%置信区间[CI]1.05,1.66,P = 0.02)。出院后90天内,有415例(30.1%)再次住院,201例(14.6%)急诊就诊,与健康素养无明显关联。

结论

健康素养较低与急性心力衰竭住院后死亡风险增加相关。健康素养与90天内再次住院或急诊就诊之间无明显关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e18/4599411/340b2ff20441/jah30004-e001799-f1.jpg

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