Suppr超能文献

结核性脊柱炎的非典型影像学特征:病例报告并文献复习

Atypical imaging features of tuberculous spondylitis: case report with literature review.

作者信息

Momjian Rita, George Mina

机构信息

Department of Radiology, Khoula Hospital, Muscat, Sultanate of Oman.

Department of Histopathology, Khoula Hospital, Muscat, Sultanate of Oman.

出版信息

J Radiol Case Rep. 2014 Nov 30;8(11):1-14. doi: 10.3941/jrcr.v8i11.2309. eCollection 2014 Nov.

Abstract

Spinal tuberculosis in its typical form that shows destruction of two adjacent vertebral bodies and opposing end plates, destruction of the intervening intervertebral disc and a paravertebral or psoas abscess, is easily recognized and readily treated. Atypical tuberculous spondylitis without the above mentioned imaging features, although seen infrequently, has been well documented. We present, in this report, a case of atypical tuberculous spondylitis showing involvement of contiguous lower dorsal vertebral bodies and posterior elements with paravertebral and epidural abscess but with preserved intervertebral discs. The patient presented in advanced stage with progressive severe neurological symptoms due to spinal cord compression. Non-enhanced magnetic resonance imaging led to misdiagnosis of the lesion as a neoplastic process. It was followed by contrast enhanced computed tomography of the chest and abdomen that raised the possibility of an infectious process and, post-operatively, histopathological examination of the operative specimen confirmed tuberculosis. This case indicates the difficulty in differentiating atypical spinal tuberculosis from other diseases causing spinal cord compression. The different forms of atypical tuberculous spondylitis reported in the literature are reviewed. The role of the radiologist in tuberculous spondylitis is not only to recognize the imaging characteristics of the disease by best imaging modality, which is contrast enhanced magnetic resonance imaging, but also to be alert to the more atypical presentations to ensure early diagnosis and prompt treatment to prevent complications. However, when neither clinical examination nor magnetic resonance imaging findings are reliable in differentiating spinal infection from one another and from neoplasm, adequate biopsy, either imaging guided or surgical biopsy is essential for early diagnosis.

摘要

典型的脊柱结核表现为两个相邻椎体及相对终板破坏、其间椎间盘破坏以及椎旁或腰大肌脓肿,易于识别且易于治疗。非典型结核性脊柱炎虽不常见,但已有充分记载,其不具备上述影像学特征。在本报告中,我们呈现了一例非典型结核性脊柱炎病例,该病例累及相邻的下胸段椎体及后部结构,伴有椎旁和硬膜外脓肿,但椎间盘未受累。患者因脊髓受压,在疾病晚期出现进行性严重神经症状。非增强磁共振成像导致该病变被误诊为肿瘤性病变。随后进行的胸部和腹部增强计算机断层扫描提示可能为感染性病变,术后手术标本的组织病理学检查确诊为结核。该病例表明,非典型脊柱结核与其他导致脊髓受压的疾病难以鉴别。本文回顾了文献中报道的不同形式的非典型结核性脊柱炎。放射科医生在结核性脊柱炎中的作用不仅是通过最佳成像方式(即增强磁共振成像)识别疾病的影像学特征,还要警惕更非典型的表现,以确保早期诊断和及时治疗,预防并发症。然而,当临床检查和磁共振成像结果均无法可靠地区分脊柱感染与肿瘤时,无论是影像引导下活检还是手术活检,充分的活检对于早期诊断至关重要。

相似文献

4
Magnetic resonance imaging of tuberculous spondylitis.结核性脊柱炎的磁共振成像
Spine (Phila Pa 1976). 1995 Nov 1;20(21):2287-92. doi: 10.1097/00007632-199511000-00005.
5
MRI diagnosis of tuberculous vertebral osteomyelitis.结核性椎体骨髓炎的磁共振成像诊断
Spine (Phila Pa 1976). 1990 Jun;15(6):462-5. doi: 10.1097/00007632-199006000-00006.
8
[Imaging diagnosis of brucella spondylitis and tuberculous spondylitis].布鲁氏菌性脊柱炎与结核性脊柱炎的影像学诊断
Zhonghua Yi Xue Za Zhi. 2018 Aug 7;98(29):2341-2345. doi: 10.3760/cma.j.issn.0376-2491.2018.29.013.
9
Spinal tuberculosis: atypical observations at MR imaging.脊柱结核:磁共振成像的非典型表现
Radiology. 1993 Nov;189(2):489-93. doi: 10.1148/radiology.189.2.8210378.

引用本文的文献

4
Miliary Tuberculosis with Paraspinal Collection and Tuberculoma.粟粒性肺结核伴椎旁脓肿及结核瘤
Am J Trop Med Hyg. 2023 Jul 3;109(2):223-224. doi: 10.4269/ajtmh.23-0083. Print 2023 Aug 2.

本文引用的文献

1
MR findings in spinal tuberculosis in an endemic country.结核病流行国家脊柱结核的磁共振成像表现
J Med Imaging Radiat Oncol. 2014;58(3):267-76. doi: 10.1111/1754-9485.12157. Epub 2014 Feb 14.
4
Spinal tuberculosis: diagnosis and management.脊柱结核:诊断与治疗
Asian Spine J. 2012 Dec;6(4):294-308. doi: 10.4184/asj.2012.6.4.294. Epub 2012 Dec 14.
6
Historical aspects of Pott's disease (spinal tuberculosis) management.Pott 病(脊柱结核)治疗的历史方面。
Eur Spine J. 2013 Jun;22 Suppl 4(Suppl 4):529-38. doi: 10.1007/s00586-012-2388-7. Epub 2012 Jul 17.
8
Minimally invasive posterior stabilization for treating spinal tuberculosis.微创后路稳定术治疗脊柱结核。
J Orthop Traumatol. 2013 Jun;14(2):143-5. doi: 10.1007/s10195-012-0184-0. Epub 2012 Feb 23.
9
Imaging of spinal metastatic disease.脊柱转移性疾病的影像学检查
Int J Surg Oncol. 2011;2011:769753. doi: 10.1155/2011/769753. Epub 2011 Nov 3.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验