Buvat J, Marcolin G, Lemaire A, Dehaene J L, Buvat-Herbaut M
Association pour l'Etude de la Pathologie de l'Appareil Reproducteur et de la Psychosomatique (EPARP), Lille.
J Urol (Paris). 1989;95(7):396-401.
"Venous incompetence" is thought to be an organic cause of impotence. Its diagnosis is usually based upon Artificial Erection Test (AET); now, the reliability of this procedure is contested. We tested it in 9 controls, 13 psychogenic impotent patients and 65 impotent patients presenting "venous incompetence" according AET (maintenance flow rate needed for erection--MFR greater than 75 ml/min). Organicity of impotence was evaluated by Nocturnal Penile Tumescence monitoring and by the results of a sex-therapy. AET reproducibility was tested in 24 cases. The interest to perform an intracavernous injection of 80 mg papaverine before AET was tested in 18 impotent patients. Our results confirm that MFR is the most reliable criterion for interpreting AET. But 15% of the impotent patients with a MFR greater than 120 ml/min, 32% of those with a MFR greater than or equal to 80 ml/min and 66% of those with a MFR between 80 and 120 ml/min were in fact psychogenic patients. Moreover, we found "excessive" MFR in 3 of the 13 psychogenic patients and one of the normal controls (160 ml/min). In 50% of our patients, AET results were not reproducible. Injecting papaverine before AET significantly reduces MFR, but false positive results do still exist. Some recent physiopathologic data suggest that AET performed after papaverine injection might logically be disturbed by stress. These data should incite to be cautious when interpreting AET results, and results of "venous incompetence" surgery.
“静脉功能不全”被认为是阳痿的一个器质性病因。其诊断通常基于人工勃起试验(AET);如今,这一检查方法的可靠性受到质疑。我们对9名对照者、13名心因性阳痿患者以及65名根据AET表现为“静脉功能不全”的阳痿患者(勃起所需维持流速——MFR大于75毫升/分钟)进行了测试。通过夜间阴茎勃起监测以及性治疗结果来评估阳痿的器质性。对24例患者测试了AET的可重复性。在18名阳痿患者中测试了在AET前进行海绵体内注射80毫克罂粟碱的意义。我们的结果证实,MFR是解释AET最可靠的标准。但是,MFR大于120毫升/分钟的阳痿患者中有15%、MFR大于或等于80毫升/分钟的患者中有32%以及MFR在80至120毫升/分钟之间的患者中有66%实际上是心因性患者。此外,我们在13名心因性患者中的3名以及1名正常对照者中发现了“过高”的MFR(160毫升/分钟)。在我们50%的患者中,AET结果不可重复。在AET前注射罂粟碱可显著降低MFR,但假阳性结果仍然存在。一些最新的病理生理学数据表明,罂粟碱注射后进行的AET可能会在逻辑上受到应激的干扰。这些数据应促使在解释AET结果以及“静脉功能不全”手术结果时保持谨慎。