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用于10至50兆赫兹生物组织模拟的明胶模型的介电特性。

Dielectric properties of gelatine phantoms used for simulations of biological tissues between 10 and 50 MHz.

作者信息

Marchal C, Nadi M, Tosser A J, Roussey C, Gaulard M L

机构信息

Centre Alexis Vautrin, Vandoeuvre les Nancy, France.

出版信息

Int J Hyperthermia. 1989 Nov-Dec;5(6):725-32. doi: 10.3109/02656738909140497.

DOI:10.3109/02656738909140497
PMID:2592786
Abstract

The use of gelatine phantoms for simulating the dielectric properties of human tissues is suggested. These phantoms are mainly made of gelatine and water and are therefore readily prepared at a low cost. They can be poured into moulds and adopt various shapes depending on the organ to be simulated. In addition, their preservation is not critical. We have studied, at 10, 27 and 50 MHz, the variations of relative permittivity and conductivity as a function of temperature between 15 and 50 degrees C. What is shown is that those values vary both as a function of gelatine concentrations and as a function of temperature. For example, at 37 degrees C and 27 MHz, variations of relative permittivity from 87 to 100 and variations of the conductivity from 0.27 to 0.45 S/m for concentrations of 10% to 40% are observed. At the above frequency, the permittivity of human and animal tissues range between 95 and 180 and the conductivity between 0.4 and 0.6 S/m. Furthermore, the addition of sodium chloride at variable concentrations enables both conductivity and permittivity values to be modified. We propose, as 'muscle-equivalent' phantoms at 27 MHz, a phantom consisting of 20% gelatine with an electrical conductivity from 0.27 to 0.48 S/m and a relative permittivity from 90 to 93 at temperatures between 15 and 50 degrees C. These gelatine, water and sodium chloride phantoms are adapted for easy and cheap simulation of most human tissues in a temperature range from 15 to 50 degrees C, for frequencies from 10 to 50 MHz.

摘要

有人建议使用明胶模型来模拟人体组织的介电特性。这些模型主要由明胶和水制成,因此很容易低成本制备。它们可以倒入模具中,并根据要模拟的器官采用各种形状。此外,它们的保存要求不高。我们在10、27和50兆赫频率下研究了相对电容率和电导率随温度在15至50摄氏度之间的变化。结果表明,这些值既随明胶浓度变化,也随温度变化。例如,在37摄氏度和27兆赫时,对于10%至40%的浓度,观察到相对电容率从87变化到100,电导率从0.27变化到0.45 S/m。在上述频率下,人体和动物组织的电容率在95至180之间,电导率在0.4至0.6 S/m之间。此外,添加不同浓度的氯化钠可使电导率和电容率值都得到改变。我们提出,作为27兆赫的“肌肉等效”模型,一种由20%明胶组成的模型,在15至50摄氏度的温度下,其电导率为0.27至0.48 S/m,相对电容率为90至93。这些明胶、水和氯化钠模型适用于在15至50摄氏度的温度范围内、10至50兆赫的频率下,轻松且低成本地模拟大多数人体组织。

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